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首页> 外文期刊>Journal of Biomechanics >An in vitro experimental study on the relationship between pulsatile tinnitus and the dehiscence/thinness of sigmoid sinus cortical plate
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An in vitro experimental study on the relationship between pulsatile tinnitus and the dehiscence/thinness of sigmoid sinus cortical plate

机译：脉腭耳鸣与乙状窦皮质板裂缝/薄度关系的体外实验研究

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摘要

Pulsatile tinnitus (PT), characterized as pulse-synchronous, is generally objective. Sigmoid sinus (SS) venous sound is widely suggested to be a possible sound source of PT. The dehiscence and thinness of SS cortical plate (CP) was commonly reported as PT pathology in previous studies, but lack quantitative or biomechanical analysis. In this study, it was aimed to quantify the relationship between venous sound and CP dehiscence/thinness using in vitro experiment. The in vitro models of SS and CP were established based on 3D-printing, with the developed pulsatile venous flow in the SS model. The generated sound signal and the vibration response at the dehiscent/thinned area were analyzed. The sound signal generated in the normal-sized dehiscence model was pulse-synchronous within 100-400 Hz, which had similar acoustic characteristics as the clinical PT sounds. It was concluded that the pulsatile venous sound is produced at TS-SS junction in case of CP dehiscence. The CP, even a thinned one can effectively diminish the venous sound and sound-generating pulsatile vibration at TS-SS junction. The CP dehiscence would induce pulse-synchronous and high pressure venous sound, as well as pulse-synchronous vibration above 20 Hz, regardless of the dehiscence size. On the contrary, the CP thinness would not induce obvious venous sound or pulsatile vibration above 20 Hz. (C) 2019 Elsevier Ltd. All rights reserved.
机译：脉动耳鸣（PT），其特征为脉冲同步，通常是物镜。 SIGMOID SINUS（SS）静脉声音被广泛建议成为PT可能的声源。 SS皮质板（CP）的裂开和薄​​度通常在先前研究中作为PT病理报告，但缺乏定量或生物力学分析。在这项研究中，旨在通过体外实验量化静脉声音和Cp裂变/薄度之间的关系。 SS和CP的体外模型是基于3D打印建立的，在SS模型中发达的脉动静脉流量。分析了所产生的声音信号和解除/稀释区域的振动响应。在正常大小的Dehciscence模型中产生的声音信号在100-400Hz内脉冲同步，其具有与临床PT声音相似的声学特性。结论是，在CP裂开的情况下，在TS-SS结产生脉动静脉声音。 CP，即使是变薄的，也可以在TS-SS结处有效地降低静脉声音和发声脉动振动。 CP Dehiscence将诱导脉冲同步和高压静脉声音，以及20 Hz以上的脉冲同步振动，而不管裂开尺寸如何。相反，CP薄度不会引起20 Hz以上的明显静脉声音或脉动振动。 （c）2019年elestvier有限公司保留所有权利。

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