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Wall shear stress fixed points in cardiovascular fluid mechanics

机译:心血管液力学中的墙剪应力固定点

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Complex blood flow in large arteries creates rich wall shear stress (WSS) vectorial features. WSS acts as a link between blood flow dynamics and the biology of various cardiovascular diseases. WSS has been of great interest in a wide range of studies and has been the most popular measure to correlate blood flow to cardiovascular disease. Recent studies have emphasized different vectorial features of WSS. However, fixed points in the WSS vector field have not received much attention. A WSS fixed point is a point on the vessel wall where the WSS vector vanishes. In this article, WSS fixed points are classified and the aspects by which they could influence cardiovascular disease are reviewed. First, the connection between WSS fixed points and the flow topology away from the vessel wall is discussed. Second, the potential role of time-averaged WSS fixed points in biochemical mass transport is demonstrated using the recent concept of Lagrangian WSS structures. Finally, simple measures are proposed to quantify the exposure of the endothelial cells to WSS fixed points. Examples from various arterial flow applications are demonstrated. (C) 2018 Elsevier Ltd. All rights reserved.
机译:大动脉复杂血液流动造成丰富的墙面剪切应力(WSS)矢量特征。 WSS作为血流动力学与各种心血管疾病的生物学之间的联系。 WSS对广泛的研究具有很大的兴趣,并且是将血流与心血管疾病相关的最受欢迎的措施。最近的研究强调了WSS的不同矢量特征。但是,WSS矢量字段中的固定点尚未受到很多关注。 WSS固定点是船墙上的点,其中WSS矢量消失。在本文中,综述了WSS的固定点以及它们可以影响心血管疾病的方面。首先,讨论了WSS固定点与远离血管壁的流动拓扑之间的连接。其次,使用最近的拉格朗日WSS结构的概念来证明时间平均WSS固定点的潜在作用。最后,提出了简单的措施来量化内皮细胞暴露于WSS的固定点。示出了各种动脉流程应用的实例。 (c)2018年elestvier有限公司保留所有权利。

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