首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Engineering anisotropic biphasic Janus‐type polymer nanofiber scaffold networks via centrifugal jet spinning
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Engineering anisotropic biphasic Janus‐type polymer nanofiber scaffold networks via centrifugal jet spinning

机译:通过离心喷射纺丝工程各向异性双相janus型聚合物纳米纤维脚手架网络

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Abstract Biphasic materials, comprised of an ordered arrangement of two different material phases within a material, have the potential for a wide variety of applications including filtration, protective clothing and tissue engineering. This study reports for the first time, a process for engineering biphasic Janus‐type polymeric nanofiber (BJPNF) networks via the centrifugal jet spinning technique. BJPNF alignment and fiber diameter was dependent on fabrication rotational speed as well as solution composition. The biphasic character of these BJPNFs, which was controlled via the rotational speed of fabrication, was confirmed at the individual nanofiber scale using energy dispersive X‐ray spectroscopy, and at the bulk, macro‐scale using attenuated total reflectance‐Fourier transform infrared spectroscopy. Biphasic character was also demonstrated at the functional level via differing affinities on either side of the BJPNF for cell attachment. Our work thus presents a method for fabricating BJPNF scaffold networks where there might be a need for different properties on either side of a material. ? 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 2455–2464, 2017.
机译:摘要两种材料,包括材料内两种不同材料阶段的有序布置,具有各种应用,包括过滤,防护服和组织工程。本研究首次报告了通过离心射流纺丝技术工程双相janus型聚合物纳米纤维(BJPNF)网络的过程。 BJPNF对准和纤维直径取决于制造转速以及溶液组合物。使用能量分散X射线光谱法在单个纳米纤维尺度上确认通过制造的旋转速度来控制这些BJPNF的双相特性,并使用衰减的总反射率 - 傅里叶变换红外光谱,在各个纳米纤维秤上确认在各个纳米纤维秤上。通过BJPNF的两侧用于细胞连接的不同亲和性,还在功能水平上证明了双相性。因此,我们的作品呈现了制造BJPNF脚手架网络的方法,其中可能需要在材料的两侧上的不同性质。还2016年Wiley期刊,Inc。J生物保解率B部分:苹果生物摩特,105B:2455-2464,2017。

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