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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Effect of wire fretting on the corrosion resistance of common medical alloys
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Effect of wire fretting on the corrosion resistance of common medical alloys

机译：钢丝发射对普通医用合金耐腐蚀性的影响

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Abstract Metallic medical devices such as intravascular stents can undergo fretting damage in vivo that might increase their susceptibility to pitting corrosion. As a result, the US Food and Drug Administration has recommended that such devices be evaluated for corrosion resistance after the devices have been fatigue tested in situations where significant micromotion can lead to fretting damage. Three common alloys that cardiovascular implants are made from [MP35N cobalt chromium (MP35N), electropolished nitinol (EP NiTi), and 316LVM stainless steel (316LVM)] were selected for this study. In order to evaluate the effect of wire fretting on the pitting corrosion susceptibility of these medical alloys, small and large fretting scar conditions of each alloy fretting against itself, and the other alloys in phosphate buffered saline (PBS) at 37°C were tested per ASTM F2129 and compared against as received or PBS immersed control specimens. Although the general trend observed was that fretting damage significantly lowered the rest potential (E r ) of these specimens ( p ??0.01), fretting damage had no significant effect on the breakdown potential (E b , p ??0.05) and hence did not affect the susceptibility to pitting corrosion. In summary, our results demonstrate that fretting damage in PBS alone is not sufficient to cause increased susceptibility to pitting corrosion in the three common alloys investigated. ? 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 2487–2494, 2017.
机译：诸如血管内支架的抽象金属医疗器械可以在体内进行烦恼，这可能会增加它们对蚀腐蚀的敏感性。因此，美国食品和药物管理局建议在装置在显着微观可能导致微动损伤的情况下进行疲劳后评估这种装置进行耐腐蚀性。三种常见的合金是心血管植入物由[MP35N钴铬（MP35N），电解抛光镍钛醇（EP NITI）和316VM不锈钢（316LVM）]进行本研究。为了评估线压力对这些医疗合金的蚀腐蚀敏感性的效果，每种合金对本身的小和大的微动疤痕条件，每次测试37℃的磷酸盐缓冲盐水（PBS）中的其他合金。 ASTM F2129并与接收或PBS浸没的对照样品进行比较。虽然观察到的一般趋势是，微动损伤显着降低了这些样本的静止电位（E·Δω.01），烦恼损伤对击穿电位没有显着影响（E B，P？＆？0.05因此，因此没有影响对蚀腐蚀的易感性。总之，我们的结果表明，单独的PBS中损伤的损伤是不足以导致在研究的三种常见合金中对蚀腐蚀的增加的敏感性。还2016 Wiley期刊，Inc.J生物保解员B部分B：苹果生物炉，105B：2487-2494,2017。

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