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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Properties of nanofiller‐loaded poly (methyl methacrylate) bone cement composites for orthopedic applications: a review
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Properties of nanofiller‐loaded poly (methyl methacrylate) bone cement composites for orthopedic applications: a review

机译：纳米填充加载聚（甲基丙烯酸甲酯）骨水泥复合材料的性质进行矫形应用：综述

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Abstract There is a large body of literature on new generations of poly (methyl methacrylate) bone cements that address one or more of the material's shortcomings. Among these are cements in which one of the constituents is a nanofiller, such as nano‐sized barium sulfate, multiwalled carbon nanotubes, natural nanoclay, mesoporous silica nanoparticles, or oleic acid‐capped silver nanoparticles. This article is a review of the literature on the properties of these nanofiller‐loaded bone cements (NFLBCs). Some key characteristics of the literature are that (1) in a number of studies, clinically relevant properties were determined, examples being maximum exotherm, setting time, fatigue life, and compressive modulus; (2) in some studies, properties were not determined in accordance with approved bone cement testing specifications, an example being fatigue life; and (3) there are a number of clinically relevant properties that were not determined in any of the studies, examples being fatigue crack propagation rate and dynamic compression creep life. These observations, as well as other considerations, suggest 12 areas for future study, such as determination of dynamic creep compliance (using nanoindentation), determination of compressive fatigue life for cements to be used in vertebral compression fracture augmentation, elucidation of toughening mechanism(s) in each type of NFLBC, and conducting well‐designed clinical trials. ? 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 1260–1284, 2017.
机译：摘要新一代聚（甲基丙烯酸甲酯）骨水泥的骨水泥有大量的文献，该骨水泥地解决了一种或多种材料的缺点。其中，其中一种组分是纳米填充剂，例如纳米尺寸硫酸钡，多污水碳纳米管，天然纳米粘土，介孔二碳纳米粒子或油酸覆盖的银纳米颗粒。本文是对这些纳米填充骨水泥（NFLBC）的性质的文献述评。文献的一些关键特征是（1）在许多研究中，确定了临床相关性质，实施例是最大放热，设定时间，疲劳寿命和压缩模量; （2）在一些研究中，不根据批准的骨水泥测试规范确定性能，这一示例是疲劳寿命; （3）在任何研究中有许多临床相关性质，实例是疲劳裂纹传播速率和动态压缩蠕变寿命。这些观察结果以及其他考虑因素建议了12个研究领域，例如动态蠕变顺应性的测定（使用纳米凸缘），测定用于椎体压缩骨折增强的水泥的压缩疲劳寿命，阐明增韧机制（S ）在每种类型的NFLBC中，并进行精心设计的临床试验。还2016 Wiley期刊，Inc。J生物保解率B部分：苹果生物摩特，105B：1260-1284,2017。

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