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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Fatigue of human dentin by cyclic loading and during oral biofilm challenge
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Fatigue of human dentin by cyclic loading and during oral biofilm challenge

机译：通过循环载荷和口腔生物膜挑战患者牙本质的疲劳

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Abstract Fatigue caused by the cyclic loads of mastication and acid attack caused by the excretion of oral biofilms are two of the most critical challenges to the success of dental restorations and their clinical service life. The objective of this investigation was to evaluate the fatigue strength of human dentin when exposed to a simultaneous challenge of cyclic loading and acidic attack from oral bacteria. Rectangular beams of coronal dentin were obtained from third molars and subjected to cyclic flexural loading while exposed to an in‐vitro microcosm biofilm model. Two different cariogenic protocols were considered and results were compared with those for control samples evaluated at neutral pH. According to the fatigue life distributions, dentin exposed to the biofilm model with 2.0% sucrose supplements pulsed twice per day caused a significant reduction in the fatigue strength ( p ??0.001) with respect to 0.2% sucrose supplements pulsed once a day, and the control environment (without biofilm). The endurance limit after biofilm exposure was 20 MPa, which is 60% lower than that of the control environment without biofilm (50 MPa). Biofilm attack of dentin increases the likelihood of restored tooth failures by fatigue and after only modest periods of exposure. ? 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 1978–1985, 2017.
机译：抽象疲劳由口腔生物膜排泄引起的咀嚼和酸侵袭引起的酸疾病是牙科修复化成功的最关键挑战以及临床使用寿命。该调查的目的是评估人类牙本质的疲劳强度，当暴露于口腔细菌的循环载荷和酸性攻击的同时挑战。从第三臼齿获得圆形冠状牙肽，并进行循环弯曲载荷，同时暴露于体外微观的生物膜模型。考虑了两种不同的致癌方案，并将结果与​​中性pH评估的对照样品进行比较。根据疲劳寿命分布，牙本质暴露于生物膜模型，每天两次脉冲两次，导致疲劳强度的显着降低（p≤≤0.001），相对于0.2％蔗糖补充剂每天脉冲一次，和控制环境（没有生物膜）。生物膜暴露后的耐久性限制为20MPa，比没有生物膜（50MPa）的对照环境低60％。牙本质的生物膜攻击增加了通过疲劳的恢复牙齿失效的可能性，并且仅在曝光时期的温度较为时期。还2016 Wiley期刊，Inc。J生物保解员B部分B：苹果生物检索物，105B：1978-1985,2017。

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