...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of bronchology & interventional pulmonology >A Prospective Outcome Assessment After Bronchoscopic Interventions for Malignant Central Airway Obstruction
【24h】

A Prospective Outcome Assessment After Bronchoscopic Interventions for Malignant Central Airway Obstruction

机译：恶性中央气道阻塞支气管镜干预后的前瞻性结果评估

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Supplemental Digital Content is available in the text. Background: A systematic assessment of comprehensive clinical outcomes after various therapeutic procedures for malignant central airway obstruction (CAO) is lacking. Methods: Patients with symptomatic malignant CAO undergoing various therapeutic bronchoscopy procedures were assessed for symptomatic and functional improvement using the Speiser Score, spirometry, 6-minute walk distance (6MWD), and St. George Respiratory Questionnaire (SGRQ) up to 3 months after the procedures. Results: A total of 83 intervention procedures were performed in 65 patients, comprising 43 (66.2%) male individuals [overall mean age, 52.4; SD, 15.4?y]. The majority of these (92.3%) was done using rigid bronchoscope under general anesthesia. Airway stenting was the most common intervention performed (56.6%), followed by mechanical debulking (26.5%), cryodebulking (6%), electrosurgical removal (4.8%), balloon dilatation (3.6%), and laser ablation (2.4%). A total of 15 complications (18.1%) were noted. Of these, 8 (53.3%) were early complications and 7 (46.7%) were late complications. Early complications included airway bleeding, hypoxia, vocal cord injury, laryngeal injury, and pneumothorax. Late complications included significant granulation tissue formation in metallic stents and lung collapse because of mucus plug. The survival rates at 4, 8, and 12 weeks were 83%, 70.7%, and 66.1%, respectively. Significant improvement was observed in dyspnea, cough, Speiser Score, 6MWD, forced expiratory volume in 1 s, forced vital capacity, and SGRQ scores at 48 hours, 4 weeks, and at 12 weeks after the procedures and no procedure-related mortality occurred. Conclusion: Various therapeutic bronchoscopic interventions, including combined modalities, provide rapid and sustained improvements in symptoms, respiratory status, exercise capacity, and quality of life in malignant CAO and have a good safety profile.
机译：文本中提供了补充数字内容。背景：缺乏在各种治疗性中央气道阻塞（CAO）后综合临床结果的系统评估。方法：使用Speiser评分，Spiromatry，6分钟步行距离（6MWD）和St. George呼吸问卷（SGRQ）患者进行症状和功能性改善，评估患有各种治疗性支气管镜检查的患者进行各种治疗支气管镜检查。程序。结果：65名患者共进行83例干预程序，包含43名（66.2％）男性个体[总体平均年龄，52.4; SD，15.4？Y]。其中大多数（92.3％）在全身麻醉下使用刚性支气管进行。气道支架是最常见的介入（56.6％），其次是机械去保存（26.5％），低温抑制（6％），电外科去除（4.8％），球囊扩张（3.6％）和激光烧蚀（2.4％）。注意到共有15个并发症（18.1％）。其中，8（53.3％）是早期并发症，7（46.7％）是晚期并发症。早期并发症包括气道出血，缺氧，声带损伤，喉损伤和气胸。晚期并发症包括由于粘液塞的金属支架和肺塌陷中的显着造粒组织形成。 4,8和12周的存活率分别为83％，70.7％和66.1％。在呼吸困难，咳嗽，Speiser评分，6MWD，迫使呼气量，48小时，48小时内，48小时后，48小时后，咳嗽，咳嗽，Speiser评分，6MWD，强迫呼气量和SGRQ分数观察到显着改善。结论：各种治疗性支气管镜干预措施，包括组合式型号，可恶性CAO的症状，呼吸状态，运动能力和生活质量的快速和持续改善，具有良好的安全性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号