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首页> 外文期刊>Journal of bronchology & interventional pulmonology >The Use of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Cytology Specimens for Programmed Death Ligand 1 Immunohistochemistry Testing in Non-Small Cell Lung Cancer
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The Use of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Cytology Specimens for Programmed Death Ligand 1 Immunohistochemistry Testing in Non-Small Cell Lung Cancer

机译：使用内核心超声引导的横向针对性细胞学检测细胞学标本，用于编程死亡配体1非小细胞肺癌免疫组织化学检测

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摘要

TRANSBRONCHIAL NEEDLE ASPIRATE (EBUS-TBNA) CYTOLOGY SPECIMENS FOR PD-L1 TESTING The National Comprehensive Cancer Network (NCCN) 2017 Clinical Practice Guidelines for non-small cell lung cancer (NSCLC) recommend concomitant diagnosis, staging, and genetic testing. In addition, guidelines recommended utilizing the least invasive biopsy procedure that offers the highest yield. EBUS-guided TBNA cytology specimens have demonstrated adequacy that is at least equivalent to that from histologic specimens for the diagnosis and staging of NSCLC. The use of EBUS-TBNA has become the procedure of first choice to diagnose and stage locally metastatic lung cancer and is recommended by multiple national and international guidelines. As such, the majority of patients with advanced NSCLC are diagnosed by small-volume cytology or biopsy specimens, and EBUS-TBNA is the most common modality of tissue acquisition; in fact, it may be the only sample available for testing throughout the patient's clinical course.
机译：跨界针头吸气（EBUS-TBNA）细胞学标本PD-L1测试全国综合癌症网络（NCCN）2017非小细胞肺癌临床实践指南（NSCLC）建议伴随诊断，分期和遗传检测。此外，指南推荐利用最少的侵入性活检程序，提供最高产量。 EBUS引导的TBNA细胞学标本已经证明了至少相当于来自组织学标本的充分性，从而具有NSCLC的诊断和分期。 EBUS-TBNA的使用已成为首选诊断和临床转移性肺癌的过程，由多个国家和国际指南推荐。因此，大多数先进的NSCLC患者被小体积细胞学或活检标本诊断，EBUS-TBNA是组织采集的最常见的形态;事实上，它可能是唯一可用于在整个患者的临床过程中进行测试的样本。

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