Replacement therapy for coronary artery bypass surgery in patients with hemophilia A and B

Kanellopoulou Theoni; Nomikou Efrosyni

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Replacement therapy for coronary artery bypass surgery in patients with hemophilia A and B

机译：血友病A和B患者冠状动脉旁路手术的替代疗法

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Abstract There are only a few cases of patients with hemophilia A and B who have undergone coronary artery bypass surgery. High levels of replacement therapy with factor concentrate either with bolus or continuous infusion are usually required pre‐operatively and during the first post‐operative days in order to maintain the coagulation deficient factor levels greater than 80% of normal. Heparinization during cardiopulmonary bypass appears to be safe and intra‐operative blood salvage using cell saver techniques reduce the need for transfusions.

机译：摘要只有少数患者血友病A和B的患者，谁经历了冠状动脉旁路手术。具有因子浓缩的高水平的替代疗法，其具有推注或连续输注通常是预先操作性的，并且在第一个操作时间内需要进行，以保持凝血缺陷的因子水平大于正常的80％。在心肺期间肝素化似乎是使用细胞节省技术的安全和术中血液抢购，这减少了输血的需要。

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来源
《Journal of cardiac surgery.》 |2018年第2期|共7页
作者
Kanellopoulou Theoni; Nomikou Efrosyni;
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作者单位

Department of Clinical Hematology‐Blood Bank and HemostasisOnassis Cardiac Surgery CenterKallithea;

Blood Bank and Hemophilia UnitHippokration General Hospital of AthensAthens Greece;

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原文格式 PDF
正文语种 eng
中图分类心脏血管和淋巴系外科学;
关键词
cardiac surgery; coronary artery bypass; factor concentrate; hemophilia; ischemic heart disease; replacement therapy;

机译：心脏手术;冠状动脉旁路;因子浓缩物;血友病;缺血性心脏病;替代疗法;

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3. Uneventful coronary artery bypass surgery without prophylactic replacement therapy in a patient with a novel heterozygous FVII gene deletion. [J] . Gallinaro L, Casonato A, Vianello F, Haemophilia: the official journal of the World Federation of Hemophilia . 2009,第5期

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Replacement therapy for coronary artery bypass surgery in patients with hemophilia A and B

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