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Intimate partner violence is associated with incident HIV infection in women in Uganda

机译：亲密伴侣暴力与乌干达妇女感染艾滋病毒有关

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Objectives: To quantify the association between intimate partner violence (IPV) and incident HIV infection in women in the Rakai Community Cohort Study between 2000 and 2009.Design and methods: Data were from the Rakai Community Cohort Study annual surveys between 2000 and 2009. Longitudinal data analysis was used to estimate the adjusted incidence rate ratio (IRR) of incident HIV associated with IPV in sexually active women aged 15-49 years, using a multivariable Poisson regression model with random effects. The population attributable fraction was calculated. Putative mediators were assessed using Baron and Kenny's criteria and the Sobel-Goodman test.Results: Women who had ever experienced IPV had an adjusted IRR of incident HIV infection of 1.55 (95% Cl 1.25-1.94, P = 0.000), compared with women who had never experienced IPV. Risk of HIV infection tended to be greater for longer duration of IPV exposure and for women exposed to more severe and more frequent IPV. The adjusted population attributable fraction of incident HIV attributable to IPV was 22.2% (95% Cl 12.5-30.4). There was no evidence that either condom use or number of sex partners in the past year mediated the relationship between IPV and HIV.Conclusion: IPV is associated with incident HIV infection in a population-based cohort in Uganda, although the adjusted population attributable fraction is modest. The prevention of IPV should be a public health priority, and could contribute to HIV prevention.
机译：目的：在2000年至2009年的Rakai社区队列研究中，量化女性的亲密伴侣暴力（IPV）与艾滋病毒感染之间的关联。设计和方法：数据来自2000年至2009年的Rakai社区队列研究年度调查。使用具有随机效应的多变量Poisson回归模型，使用数据分析来估计15-49岁的性活跃女性中与IPV相关的HIV的调整后的发病率比率（IRR）。计算了人口归因分数。使用Baron和Kenny的标准以及Sobel-Goodman检验对推定的介体进行了评估。结果：与IPV相比，曾经历IPV的女性的HIV感染后IRR调整后为1.55（95％Cl 1.25-1.94，P = 0.000）。从未经历过IPV的人。随着IPV暴露时间的延长和暴露于更严重，更频繁IPV的妇女，HIV感染的风险往往更大。归因于IPV的HIV感染事件的调整后人口比例为22.2％（95％Cl 12.5-30.4）。没有证据表明在过去的一年中使用安全套或性伴侣的数量介导了IPV与HIV之间的关系。结论：尽管调整后的人群可归因比例是乌干达，但IPV与乌干达一个以人群为基础的队列中的HIV感染有关。谦虚。预防IPV应该是公共卫生的优先事项，并可能有助于预防HIV。

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