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Adipose tumors of the heart

机译:心脏的脂肪肿瘤

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Abstract Background Primary cardiac adipose tumors are rare. There are two distinct pathologically defined entities that represent this tumor type: lipoma and lipomatous hypertrophy of the interatrial septum (LHIS). We present a single‐center experience with these tumors and demonstrate that the location may not correspond to the pathologic diagnosis. Methods A retrospective review of a prospectively collected cardiac surgery database from January 1990 to July 2016 identified 254 cases of surgically treated primary cardiac tumors at our Institution. Of these, 06/254 (2%) were primary adipose tumors. Results In 3/6 (50%) cases, patients were asymptomatic or had symptoms referable to other known intracardiac lesions. Five patients (83%) had preserved ventricular function. In 4/6 cases (67%), the tumor was identified preoperatively. All patients presented in New York Heart Association functional class ≤2. Pathologic diagnosis of LHIS was made in 5/6 cases (83%), with 2/5 LHIS (40%) located in the interatrial septum. A bovine pericardial patch was utilized for reconstruction following tumor resection in 3/6 cases (50%). Mean cardiopulmonary bypass time was 88?±?43?min. All the patients tolerated the procedure well without any postoperative complications. Conclusions Primary cardiac adipose tumors are responsible for a small portion of all primary heart tumors. Surgical resection provided excellent outcomes, and did not affect cardiac performance, in spite of the need for extensive resections. LHIS was identified in locations other than the interatrial septum and was usually symptomatic.
机译:摘要背景初级心脏脂肪瘤是罕见的。存在两个不同的病理定义实体,其代表这种肿瘤类型:血脂瘤和血液间隔(LHI)的脂质肥大。我们提出了一种与这些肿瘤的单中心体验,并证明该位置可能与病理诊断不相对应。方法回顾性审查1990年1月至2016年7月从2000年1月到2016年7月的前瞻性心脏手术数据库确定了254例外科手术治疗原发性心脏肿瘤。其中,06/254(2%)是初级脂肪肿瘤。结果3/6(50%)病例,患者无症状或有其他已知的心内病变可引起的症状。五名患者(83%)保存了心室功能。在4/6例(67%)中,术前鉴定了肿瘤。所有患者均在纽约心脏关联功能级≤2。 LHI的病理诊断是在5/6病例(83%)中进行的,2/5 LHI(40%)位于间隔内隔。在3/6病例(50%)中,使用牛心包贴片进行肿瘤切除后的重建。意味着心肺旁路时间为88?±43?min。所有患者均可妥善潜水,没有任何术后并发症。结论原发性心脏脂肪肿瘤对所有原发性心脏肿瘤的一小部分负责。外科切除术提供了出色的结果,并且尽管需要广泛切除,但不影响心脏表现。 LHI在外处室隔膜以外的地点鉴定,通常是对症的。

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