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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Acute cardiac effects of high dose steroid treatment: A speckle tracking echocardiography study
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Acute cardiac effects of high dose steroid treatment: A speckle tracking echocardiography study

机译：高剂量类固醇处理的急性心脏作用：散斑跟踪超声心动图研究

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Purpose High-dose steroid therapy (HDST) has frequent side-effects that appear at its cessation and depend on its dose. However, there is a lack of studies about the acute effects of HDST on cardiac function in adult patients. Methods We included in this study 30 patients who underwent HDST (intravenously at doses ranging from 250 to 1000 mg) and 30 healthy control subjects with similar demographic and clinical characteristics, between September and December 2016. Echocardiographic measurements were made before and during the first 3 hours after the end of treatment, and results were compared between patients and controls. Results There was no difference in baseline biochemical and echocardiographic characteristics between the patient and control groups. While left ventricular global longitudinal strain (LVGLS) and strain rate E were higher after treatment, no significant change was observed in conventional echocardiographic variables. Conclusions LVGLS, but not conventional echocardiographic variables, showed an increase in cardiac systolic function at the acute phase of HDST.
机译：目的高剂量类固醇疗法（HDST）经常出现在其停止时的副作用，并取决于其剂量。然而，缺乏关于HDST对成年患者心脏功能的急性作用的研究。本研究中纳入本研究的方法30患者在2016年9月和12月间在250岁的健康对照组和临床特征中静脉注射的30名健康对象和临床特征。在前3之前和期间进行过超声心动图测量治疗结束后的小时数，患者和对照之间的结果进行了比较。结果患者和对照组之间的基线生化和超声心动图特征没有差异。虽然在处理后左心室全局纵向菌株（LVGLS）和应变速率E更高，但在常规超声心动图变量中没有观察到显着变化。结论LVGLS，但不是常规超声心动图变量，显示高清急性期心脏收缩功能的增加。

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