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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Extended 36‐joint sonographic examination: What it reveals about bone erosions in patients with rheumatoid arthritis
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Extended 36‐joint sonographic examination: What it reveals about bone erosions in patients with rheumatoid arthritis

机译:延长36个关节超声检查:患有类风湿性关节炎患者的骨腐蚀揭示了什么

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Abstract Purpose To identify joints commonly exhibiting bone erosions using an extended 36‐joint sonographic (US) examination in patients with rheumatoid arthritis (RA) and to study bone erosion in relation to US‐detected joint inflammation. Methods In this cross‐sectional study, power Doppler (PD) and gray‐scale (GS) joint inflammation scores (semi‐quantitative [0‐3] grading) at each joint recess were summed to obtain a combined US score (CUS). Bone erosion was scored as present/absent. Generalized Estimating Equations were used to compare mean US scores between joint recesses with and without bone erosion. Results Bone erosion was found in 144/1080 (13.3%) joints and 189/1800 (10.5%) joint recesses in 30 RA patients. The five joints most frequently associated with bone erosion were: wrist, n = 49/144 (34.0%); first MTPJ, n = 19/144 (13.2%); thumb IPJ, n = 13/144 (9.0%); second MCPJ, n = 11/144 (7.6%); and third MCPJ, n = 11/144 (7.6%). Mean (95% CI) US scores for joint recesses with and without bone erosion were PD: 0.36 (0.21, 0.50) vs 0.01 (0.00, 0.02); GS: 1.77 (1.54, 2.00) vs 0.47 (0.40, 0.55); and CUS: 2.13 (1.78, 2.47) vs 0.49 (0.41, 0.57) (all differences significant at P ?.001). Conclusion The five joints most frequently showing bone erosion were identified. Joint recesses with bone erosion are more likely to exhibit greater PD and GS joint inflammation severity.
机译:摘要目的,以鉴定通常在类风湿性关节炎(RA)患者患者中使用延长的36关节声学(US)检查和研究与美国检测联的关节炎症有关的骨腐蚀的骨腐蚀。在该横截面研究中,在每个关节凹槽中,功率多普勒(Pd)和灰度(GS)关节炎症评分(半定量[0-3]分级)总结得以获得组合的美国得分(CU)。骨腐蚀被评分为现在/缺席。广义估计方程用于比较与骨腐蚀的关节凹槽之间的比分。结果在144/1080(13.3%)和189/1800(10.5%)在30名RA患者中发现骨腐蚀。最常与骨侵蚀相关的五个关节是:手腕,n = 49/144(34.0%);第一个mtpj,n = 19/144(13.2%);拇指IPJ,n = 13/144(9.0%);第二个MCPJ,n = 11/144(7.6%);第三个mcpj,n = 11/144(7.6%)。平均值(95%CI)与骨腐蚀的关节凹槽的美国分数为PD:0.36(0.21,0.50)vs 0.01(0.00,0.02); GS:1.77(1.54,2.00)Vs 0.47(0.40,0.55);和CUS:2.13(1.78,2.47)与0.49(0.41,0.57)(P& 001)的所有差异。结论鉴定了最常见的骨腐蚀的五个关节。具有骨侵蚀的关节凹槽更可能表现出更大的Pd和Gs关节炎症严重程度。

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