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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Transcranial Doppler waveform changes due to increased cerebrovascular resistance and raised intracranial pressure in a patient with cirrhosis: A difference in shapes, not in numbers
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Transcranial Doppler waveform changes due to increased cerebrovascular resistance and raised intracranial pressure in a patient with cirrhosis: A difference in shapes, not in numbers

机译:经颅多普勒波形由于脑血管血管耐药性增加,肝硬化患者升高:形状的差异,而不是数量

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摘要

Abstract We report and discuss a case that illustrate the clinical utility of transcranial Doppler (TCD) ultrasound in a patient with cirrhosis. A 43‐year‐old female presented with acute decompensation of cirrhosis with hepatic encephalopathy, requiring mechanical ventilation. TCD showed low diastolic flow velocities and high pulsatility index (PI) consistent with increased cerebrovascular resistance (CVR). The flow velocities and PI normalized over a period of few days and correlated well with neurological improvement after treatment. Subsequently, the patient developed a large intracerebral hemorrhage with mass effect. The TCD measurements in intracranial hypertension were similar to those with cirrhosis and hepatic encephalopathy. However, the windkessel notch in the systolic phase of TCD waveform, related to the distensibility of arterial wall, was absent during raised intracranial pressure (ICP). The absence of a windkessel notch may help to differentiate a high downstream resistance due to raised ICP from increased CVR.
机译:摘要我们报告并讨论了说明经颅多普勒(TCD)超声在肝硬化患者中的临床效用的情况。一位43岁女性患有肝脏脑病的肝硬化急性失代偿,需要机械通气。 TCD显示出与增加的脑血管抗性(CVR)的低舒张流流速和高脉冲性指数(PI)一致。流速和Pi在几天内归一化,并在治疗后与神经改善相关。随后,患者产生大量脑内出血,质量效应。颅内高血压中的TCD测量与肝硬化和肝脑病的TCD测量相似。然而,在升高的颅内压(ICP)中,不存在与动脉壁的延伸性有关的TCD波形的收缩阶段的挡风玻璃凹口。缺乏挡风玻璃凹口可能有助于区分由于CVR增加的升高的ICP引起的高下游抗性。

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