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首页> 外文期刊>Journal of clinical sleep medicine: JCSM : official publication of the American Academy of Sleep Medicine >Obstructive Sleep Apnea in a Severely Obese Child With Combined Central Sleep Apnea and Sleep-Related Hypoventilation Disorder Caused by a Medullary Tumor
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Obstructive Sleep Apnea in a Severely Obese Child With Combined Central Sleep Apnea and Sleep-Related Hypoventilation Disorder Caused by a Medullary Tumor

机译：阻塞性睡眠呼吸暂停在一个严重的肥胖儿童中，中央睡眠呼吸暂停和睡眠相关的患有髓质肿瘤引起的睡眠相关的下呼吸障碍症

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摘要

A medullary tumor is a relatively rare disease that causes severe and complicated respiratory disorders, including sleep-related breathing disorders, due to dysregulation of respiratory control. A severely obese 12-year-old male was admitted to our hospital for worsening dyspnea and received a diagnosis of type II respiratory failure. Although obstructive sleep apnea (OSA) and/or obesity hypoventilation syndrome were suspected, a polysomnogram obtained during a nap (nap study) revealed central sleep apnea (CSA) and sleep-related hypoventilation disorder (SRHD) in addition to OSA. Brain magnetic resonance imaging showed a mass in the medulla oblongata. The patient received a diagnosis of CSA/SRHD caused by a medullary tumor, and with OSA. A partial brainstem tumor resection was performed. Noninvasive positive airway pressure therapy was initiated, and was continued after surgery. However, the patient died unexpectedly, 20 months after surgery. When children with sleep problems caused by OSA present with atypical symptoms of OSA, a neurological examination and polysomnography should be conducted to detect CSA and SRHD.
机译：髓质肿瘤是一种相对罕见的疾病，导致严重和复杂的呼吸系统障碍，包括睡眠相关的呼吸障碍，由于呼吸控制的失调。一个严重肥胖的12岁的男性被录取到我们的医院恶化呼吸困难，并获得II型呼吸衰竭的诊断。虽然怀疑阻塞性睡眠呼吸暂停（OSA）和/或肥胖呼吸悬浮综合征，但除了OSA之外，在午睡（NAP研究）中获得的多肌导图揭示了中枢睡眠呼吸暂停（CSA）和睡眠相关的血吸障碍障碍（SRHD）。脑磁共振成像显示髓质椭圆形的质量。患者接受了由髓质肿瘤和OSA引起的CSA / SRHD的诊断。进行部分脑干肿瘤切除。开始非侵入性正气道压力疗法，手术后继续。然而，患者在手术后20个月内意外死亡。当患有OSA的OSA引起的睡眠问题的儿童患有OSA的非典症症状时，应进行神经系统检查和多面体摄影来检测CSA和SRHD。

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