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The erythrocyte sedimentation rate in HIV: a neglected parameter?

机译:HIV中的红细胞沉降率:一个被忽略的参数?

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摘要

Accepted wisdom in the assessment of a person with HIV is that the erythrocyte sedimentation rate (ESR) is not a useful test. Although initially considered as an indicator of disease progression [1,2], later studies disagreed [3] or demonstrated only a negligible fall in CD4 cell count with rising ESR [4].Although the use of ESR to predict the development of AIDS is still under investigation in the developing world [5], it is considered less helpful in countries with easy access to CD4 cell monitoring. The ESR does not predict acute illness in HIV [6] and when measured, it is not uncommon to discover values in triple figures in otherwise asymptomatic individuals with normal CD4 cell counts: in one recent study, 27% of Tanzanian patients with an ESR more than 120 mm/h still had a CD4 cell count greater than 200/mul [7]. As such, it is rare to find recent data on ESR levels in HIV-positive people except from Africa [5,7,8], and it has not been published as an independent variable in any of the large prospective cohort studies.
机译:评估HIV感染者的公认观点是,红细胞沉降率(ESR)并不是有用的测试。虽然最初被认为是疾病进展的指标[1,2],但后来的研究却不同意[3]或仅显示出可忽略的CD4细胞计数随ESR升高而下降[4]。尽管使用ESR来预测艾滋病的发展是仍在发展中国家进行研究[5],在容易获得CD4细胞监测的国家中,它被认为不太有用。 ESR不能预测HIV的急性病[6],经测量,发现CD4细胞计数正常的无症状个体的三位数数值并不罕见:在最近的一项研究中,坦桑尼亚有27%的ESR患者更多大于120 mm / h的CD4细胞数仍大于200 / mul [7]。因此,除了非洲之外,很少有关于HIV阳性人群的ESR水平的最新数据[5,7,8],并且在任何大型前瞻性队列研究中均未将其作为独立变量发表。

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  • 来源
    《AIDS》 |2010年第18期|共3页
  • 作者

    Lowe DM;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 传染病;
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