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首页> 外文期刊>AIDS >HIV-1 seroreversion following antiretroviral therapy in an HIV-infected child initially presenting with acquired immunodeficiency syndrome.
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HIV-1 seroreversion following antiretroviral therapy in an HIV-infected child initially presenting with acquired immunodeficiency syndrome.

机译:在最初表现为获得性免疫缺陷综合症的HIV感染儿童中,抗逆转录病毒疗法后HIV-1血清逆转。

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摘要

In adults, HIV-1 seroreversion following antiretroviral therapy is rare and has been reported only in patients who were treated shortly after primary HIV-1 infection [1-3]. In HIV-1 infected infants, seroreversion after suppression of viral replication appears to be more frequent than in adults [4,5]. However, these infants were asymptomatic or mildly symptomatic and were treated in the first 3 months of life. After this time period, especially when the clinical picture of AIDS has been developed, seroreversion following antiretroviral therapy has not been reported yet. Here, we report the unusual case of seroreversion following antiretroviral therapy in a child vertically infected with HIV initially presenting with AIDS defining conditions.
机译:在成年人中,抗逆转录病毒疗法后的HIV-1血清逆转很少见,仅在原发HIV-1感染后不久接受治疗的患者中有报道[1-3]。在感染了HIV-1的婴儿中,抑制病毒复制后的血清逆转似乎比成人更频繁[4,5]。但是,这些婴儿无症状或轻度症状,并且在生命的头3个月内接受了治疗。在这段时间之后,特别是当艾滋病的临床情况已经发展时,尚未报道抗逆转录病毒疗法后的血清逆转。在这里,我们报道了一名儿童的抗逆转录病毒治疗后出现血清逆转的异常情况,该儿童最初感染了艾滋病,最初具有艾滋病的定义条件。

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