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Immune reconstitution inflammatory syndrome as histoplasmosis osteomyelitis in South America

机译:南美地区由于组织重构性骨髓炎而导致的免疫重建炎症综合症

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摘要

Histoplasma is a dimorphic fungus that presents; as an opportunistic infection frequently reported in HIV-infected patients who reside in endemic areas. In the Americas, Histoplasma capsulatum is the predominant form and it is most frequently found in North and Central America. The most common clinical presentation is pulmonary histoplasmosis; however, in immunosuppressed patients, other organs can be affected with no lung involvement. A 44-year-old woman, who was HIV-positive, presented to our ward with a 3-week history of bilateral hand and foot pain. The patient had been on antiretroviral therapy (ART) for her HIV for the past 7 years. However, she stopped the treatment 2 months before the presentation to our hospital. Her CD4+ cell count at the time of presentation was 12 cells/(xl and her HIV viral load was 121 785 copies/ml. Initial bilateral hand and foot radiographs showed no abnormalities.
机译:组织胞浆菌是一种双态真菌。居住在地方性地区的HIV感染患者中经常报道这种机会性感染。在美洲,荚膜组织胞浆菌是主要形式,在北美和中美洲最常见。最常见的临床表现是肺组织胞浆菌病。但是,在免疫抑制的患者中,其他器官可能会受到影响而无肺部感染。一名HIV阳性的44岁女性向我们的病房介绍了3周的双侧手足痛史。该患者在过去7年中一直接受HIV抗逆转录病毒疗法(ART)。但是,她在就诊前两个月就停止了治疗。报告时她的CD4 +细胞计数为12个细胞/(xl),她的HIV病毒载量为121785拷贝/ ml。最初的双侧手足影像学检查未发现异常。

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