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首页> 外文期刊>Journal of drugs in dermatology: JDD >Comparison of Two Swiss-Designed Hyaluronic Acid Gels: Six-Month Clinical Follow-Up
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Comparison of Two Swiss-Designed Hyaluronic Acid Gels: Six-Month Clinical Follow-Up

机译：两种瑞士设计的透明质酸凝胶的比较：六个月的临床随访

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摘要

The aim of this paper is to compare 2 hyaluronic acid gel fillers from the same Swiss manufacturer and with the same indications: filling of line wrinkles and folds. The products differ by their cross-linking process. With very simple easy-to-reproduce tests, cohesivity and resistance to traction forces were examined. Also, both gels were injected under ultrasound control in the mid reticular dermis of three subjects. The papules were controlled under ultrasound and biopsies at DO and D15. Results showed significant differences between the 2 gels in all the tests. The new gel, manufactured with a lower-crosslinking density, seems to benefit from better integration in the tissue of the mid reticular dermis and to have a more cohesive nature than its comparator from a previous crosslinking technology. Under clinical observation, the range of new products present excellent tissue integration properties.
机译：本文的目的是将2个透明质酸凝胶填料与相同的瑞士制造商进行比较，适应相同的指示：线皱纹和折叠的填充。 产品因其交叉连接过程而异。 通过非常简单的易于再现的测试，检查了粘合性和对牵引力的抵抗力。 此外，在三个受试者的中网状皮疹中，在超声控制下注射了两种凝胶。 丘疹在OT和D15的超声和活组织检查下控制。 结果表明，所有测试中2凝胶之间的显着差异。 以较低交联密度制造的新凝胶似乎受益于中网状皮肤的组织中的更好的整合，并且具有比其先前交联技术的比较器更具凝聚力的性质。 在临床观察下，新产品的范围具有出色的组织积分性能。

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