Two Multicenter, Randomized, Double-Blind, Parallel Group Comparison Studies of a Novel Enhanced Lotion Formulation of Halobetasol Propionate, 0.05% Versus Its Vehicle in Adult Subjects With Plaque Psoriasis

Pariser David; Bukhalo Michael; Guenthner Scott; Kempers Steven; Shideler Stephen; Gold Linda Stein; Tschen Eduardo; Berg Jim; Ferdon Mary Beth; Dromgoole Syd

首页> 外文期刊>Journal of drugs in dermatology: JDD >Two Multicenter, Randomized, Double-Blind, Parallel Group Comparison Studies of a Novel Enhanced Lotion Formulation of Halobetasol Propionate, 0.05% Versus Its Vehicle in Adult Subjects With Plaque Psoriasis

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Two Multicenter, Randomized, Double-Blind, Parallel Group Comparison Studies of a Novel Enhanced Lotion Formulation of Halobetasol Propionate, 0.05% Versus Its Vehicle in Adult Subjects With Plaque Psoriasis

机译：二种多中心，随机，双盲，并联小型卤代醇丙酸酚丙酸盐制剂的新型增强乳液配方，与其在成人受试者中的斑块牛皮癣的载体

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Background: A novel lotion formulation of halobetasol propionate, 0.05% (HBP Lotion) with enhanced vehicle characteristics of a cream while preserving the ease of use and cosmetic elegance of a lotion has been developed to treat plaque psoriasis.

机译：背景技术：卤代醇丙酸酯的新乳液制剂，0.05％（HBP乳液）具有增强的奶油的载体特性，同时保存易于使用和化妆品的化妆品的化妆品，以治疗斑块牛皮癣。

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《Journal of drugs in dermatology: JDD》 |2017年第3期|共7页
作者
Pariser David; Bukhalo Michael; Guenthner Scott; Kempers Steven; Shideler Stephen; Gold Linda Stein; Tschen Eduardo; Berg Jim; Ferdon Mary Beth; Dromgoole Syd;
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作者单位

Virginia Clin Res Inc Norfolk VA USA;

Altman Dermatol Associates Arlington Hts IL USA;

Indiana Clin Trials Ctr PC Plainfield IN USA;

Minnesota Clin Study Ctr Fridley MN USA;

Forefront Dermatol Carmel IN USA;

Henry Ford Hlth Syst Detroit MI USA;

Acad Dermatol Associates Albuquerque NM USA;

Therapeutics Inc San Diego CA 92123 USA;

Therapeutics Inc San Diego CA 92123 USA;

Therapeutics Inc San Diego CA 92123 USA;

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正文语种 eng
中图分类药学;
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1. Two Multicenter, Randomized, Double-Blind, Parallel Group Comparison Studies of a Novel Enhanced Lotion Formulation of Halobetasol Propionate, 0.05% Versus Its Vehicle in Adult Subjects With Plaque Psoriasis [J] . Pariser David, Bukhalo Michael, Guenthner Scott, Journal of drugs in dermatology: JDD . 2017,第3期

机译：二种多中心，随机，双盲，并联小型卤代醇丙酸酚丙酸盐制剂的新型增强乳液配方，与其在成人受试者中的斑块牛皮癣的载体
2. A phase 2, multicenter, double-blind, randomized, vehicle-controlled clinical study to compare the safety and efficacy of a halobetasol propionate 0.01% lotion and halobetasol propionate 0.05% cream in the treatment of plaque psoriasis [J] . Kerdel Francisco A., Draelos Zoe D., Tyring Stephen K., The Journal of dermatological treatment . 2019,第1a8期

机译：2阶段，多中心，双盲，随机，车辆控制的临床研究，以比较卤代醇丙酸酯0.01％乳液和卤代萘醇治疗斑块牛皮癣的0.05％乳膏的安全性和疗效
3. Efficacy and safety of apremilast in subjects with moderate to severe plaque psoriasis: Results from a phase II, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison study [J] . PappK.A., KaufmannR., Tha?iD., Journal of the European Academy of Dermatology and Venereology: JEADV . 2013,第3期

机译：普瑞司特在中度至重度斑块状牛皮癣患者中的疗效和安全性：II期，多中心，随机，双盲，安慰剂对照，平行组，剂量比较研究的结果
4. Safety and Efficacy of a Halobetasol 0.01/Tazarotene 0.045 Fixed Combination Lotion in the Treatment of Moderate-to-severe Plaque Psoriasis: A Comparison with Halobetasol Propionate 0.05 Cream [O] . Neal D. Bhatia, David M. Pariser, Leon Kircik, 2018

机译：0.01％/他扎罗汀0.045％他扎罗汀0.045％固定组合洗剂治疗中度至重度斑块状牛皮癣的安全性和有效性：与丙酸卤倍他索0.05％乳膏的比较
5. >Impact of Halobetasol Propionate and Tazarotene Lotion 0.01/0.045 in the Management of Plaque Psoriasis in Adults [O] . Vidhatha Reddy, Bridget Myers, Eric J Yang, 2020

机译：> Halobetasol丙酸盐和塔拉替烯乳液的影响0.01％/ 0.045％在成人斑块牛皮癣中的管理中

Two Multicenter, Randomized, Double-Blind, Parallel Group Comparison Studies of a Novel Enhanced Lotion Formulation of Halobetasol Propionate, 0.05% Versus Its Vehicle in Adult Subjects With Plaque Psoriasis

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