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首页> 外文期刊>Journal of cutaneous pathology >A case of extramedullary hematopoiesis presenting as hemorrhagic panniculitis and evolving in acute myeloid leukemia
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A case of extramedullary hematopoiesis presenting as hemorrhagic panniculitis and evolving in acute myeloid leukemia

机译：蛋白血液血液呈现出出血性胰岛炎，在急性髓性白血病中发展

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Abstract Extramedullary hematopoiesis (EMH) in adults is a rare event, usually associated with myeloid disorders, and can be the first sign of chronic myelomonocytic leukemia. We report a case of EMH presenting as a hemorrhagic panniculitis in a patient who did not apparently present any myeloid disorders. The patient received previous chemotherapy for mantle cell lymphoma localized to the large bowel and had been in complete remission for 3?years. The diagnosis of EMH was achieved after a deep incisional biopsy of a nodule from the thigh, and with pathological examination that included immunohistochemical studies. After a follow‐up of 14 months, the patient developed an acute myeloid leukemia, classified as therapy‐related myeloid neoplasm, according to the 2016 World Health Organization (WHO) classification of hematological malignancies. As shown by the rare cases described in literature, the presence of cutaneous EMH should always be a trigger for investigating the patient's hematological system; also, in our experience, a long follow‐up is mandatory.
机译：摘要成年人的摘要喹甲血目（EMH）是一种罕见的事件，通常与骨髓紊乱有关，并且可以是慢性骨髓细胞白血病的第一个标志。我们举报了一个EMH作为一种没有显然呈现任何髓样疾病的患者出血性胰岛炎的案例。该患者在局部肠道局部化的地幔细胞淋巴瘤中获得了先前的化疗，并在3年​​内完全缓解了缓解。在从大腿的结节的深度切口活检后和病理检查包括免疫组织化学研究，达到EMH的诊断。根据2016年世界卫生组织（WHO）血液恶性肿瘤分类，患者患有急性髓性白血病，归类为治疗相关的骨髓肿瘤。如文学中所述的罕见情况所示，皮肤EMH的存在应始终是调查患者血液系统的触发;此外，在我们的经验中，长期以来是强制性的。

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