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首页> 外文期刊>Belgian Journal of Zoology >The ultrastructural immunolocalization of loricrinin the hairy epidermis of the platypus(Ornithorhynchus anatinus, Monotremata)indicates it contributes to the formation of the cell corneous envelope
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The ultrastructural immunolocalization of loricrinin the hairy epidermis of the platypus(Ornithorhynchus anatinus, Monotremata)indicates it contributes to the formation of the cell corneous envelope

机译：Loricrinin在鸭嘴兽的毛状表皮中的超微结构免疫定位表明它有助于细胞角膜包膜的形成

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摘要

The fine localization of loricrin, a major protein of the cell corneous envelope, is known for the epidermis of few spe-cies of placental mammals. The localization of this protein has been studied by immunocytochemistry in the hairy epidermis (orthokeratotic) of the platypus, a representative of monotremes, and compared with the localization of the protein in the epidermis of placental mammals. In the hairy epidermis small keratohyaline granules of 0.1-0.3μm are present in transitional cells of the stra-tum granulosum. An anti-loricrin antibody labels the pale component of keratohyaline granules, the corneous mass of transitional corneocytes, and mainly the corneous cell envelope of corneocytes in the stratum corneum. The last pattern resembles that of the hairy epidermis of placental mammals and differs from the diffuse distribution of loricrin previously described in the parakeratotic epidermis of the platypus. The study confirms that the final pattern of distribution of loricrin in the hairy epidermis of the platypus is as previously observed in corneocytes of placental mammals.
机译：Loricrin是细胞角膜包膜的主要蛋白质，它的精细定位因胎盘哺乳动物的少数表皮而闻名。已经通过免疫细胞化学在鸭嘴兽的毛状表皮（角膜塑形）中研究了该蛋白的定位，该表皮是单足动物的代表，并与该蛋白在胎盘哺乳动物表皮中的定位进行了比较。在毛状表皮中，层状颗粒的过渡细胞中存在0.1-0.3μm的小角膜透明质酸颗粒。抗-loricrin抗体标记角膜透明质酸颗粒的苍白成分，过渡性角质细胞的角质，并且主要标记角质层中角质细胞的角质细胞包膜。最后一种模式类似于胎盘哺乳动物的毛状表皮，并且不同于先前在鸭嘴兽的角化不全表皮中描述的萝莉汀的分散分布。这项研究证实，在鸭嘴兽的毛状表皮中loricrin的最终分布模式与以前在胎盘哺乳动物的角质细胞中观察到的一样。

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