Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients

Delic Denis; Wolk Kerstin; Schmid Ramona; Gabrielyan Ogsen; Christou Demetrios; Rieber Kathrin; Rolser Marcel; Jakob Ines; Wiech Franziska; Griesser Manuela; Wohnhaas Christian; Kokolakis Georgios; Witte-Haendel Ellen; Baum Patrick; Sabat Robert

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Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients

机译：牛皮癣患者皮肤的集成microRNA / mRNA表达分析

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Background: Psoriasis is a chronic inflammatory disease characterized by demarcated, raised, and scaling skin lesions. It often serves as a model for immune-mediated disorders. Gene expression profiling of affected skin has allowed insights into psoriasis pathogenesis. However, the mechanisms leading to specific mRNA expression alterations in psoriasis are barely understood.

机译：背景：牛皮癣是一种慢性炎症性疾病，其特征在于划定，提出和缩放皮肤病变。它通常用作免疫介导的疾病的模型。受影响皮肤的基因表达分析使洞察力有洞察力。然而，导致牛皮癣的特异性mRNA表达改变的机制几乎没有理解。

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来源
《Journal of dermatological science》 |2020年第1期|共12页
作者
Delic Denis; Wolk Kerstin; Schmid Ramona; Gabrielyan Ogsen; Christou Demetrios; Rieber Kathrin; Rolser Marcel; Jakob Ines; Wiech Franziska; Griesser Manuela; Wohnhaas Christian; Kokolakis Georgios; Witte-Haendel Ellen; Baum Patrick; Sabat Robert;
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作者单位

Boehringer Ingelheim Pharma GmbH &

Co KG Translat Med &

Clin Pharmacol Birkendorfer Str 65 D;

Charite Univ Med Berlin Psoriasis Res &

Treatment Ctr Charitepl 1 D-10117 Berlin Germany;

Boehringer Ingelheim Pharma GmbH &

Co KG Translat Med &

Clin Pharmacol Birkendorfer Str 65 D;

Boehringer Ingelheim Pharma GmbH &

Co KG Translat Med &

Clin Pharmacol Birkendorfer Str 65 D;

Charite Univ Med Berlin Psoriasis Res &

Treatment Ctr Charitepl 1 D-10117 Berlin Germany;

Boehringer Ingelheim Pharma GmbH &

Co KG Translat Med &

Clin Pharmacol Birkendorfer Str 65 D;

Boehringer Ingelheim Pharma GmbH &

Co KG Translat Med &

Clin Pharmacol Birkendorfer Str 65 D;

Boehringer Ingelheim Pharma GmbH &

Co KG Translat Med &

Clin Pharmacol Birkendorfer Str 65 D;

Boehringer Ingelheim Pharma GmbH &

Co KG Translat Med &

Clin Pharmacol Birkendorfer Str 65 D;

Boehringer Ingelheim Pharma GmbH &

Co KG Translat Med &

Clin Pharmacol Birkendorfer Str 65 D;

Boehringer Ingelheim Pharma GmbH &

Co KG Translat Med &

Clin Pharmacol Birkendorfer Str 65 D;

Charite Univ Med Berlin Psoriasis Res &

Treatment Ctr Charitepl 1 D-10117 Berlin Germany;

Charite Univ Med Berlin Psoriasis Res &

Treatment Ctr Charitepl 1 D-10117 Berlin Germany;

Boehringer Ingelheim Pharma GmbH &

Co KG Translat Med &

Clin Pharmacol Birkendorfer Str 65 D;

Charite Univ Med Berlin Psoriasis Res &

Treatment Ctr Charitepl 1 D-10117 Berlin Germany;

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原文格式 PDF
正文语种 eng
中图分类皮肤病学与性病学;
关键词
Psoriasis; Gene expression; microRNA; Integrated; Analysis;

机译：牛皮癣;基因表达;microRNA;综合;分析;

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专利

1. Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients [J] . Delic Denis, Wolk Kerstin, Schmid Ramona, Journal of dermatological science . 2020,第1期

机译：牛皮癣患者皮肤的集成microRNA / mRNA表达分析
2. Integration of microRNA and mRNA expression profiles in the skin of systemic sclerosis patients [J] . Bin Zhou, Xiao Xia Zuo, Yi Sha Li, Scientific reports. . 2017,第1期

机译：MicroRNA和mRNA表达谱系在系统性硬化症患者皮肤中的整合
3. Integrated analysis of microRNA and mRNA expression profiles in the left atrium of patients with nonvalvular paroxysmal atrial fibrillation: Role of miR-146b-5p in atrial fibrosis [J] . Wang Jiangang, Wang Yongyu, Han Jie, Heart rhythm: the official journal of the Heart Rhythm Society . 2015,第5期

机译：非瓣膜性阵发性心房颤动患者左心房microRNA和mRNA表达谱的综合分析：miR-146b-5p在心房纤维化中的作用
4. A network-based analysis of ischemic stroke using parallel microRNA-mRNA expression profiles [C] . Yingying Wang, Yunpeng Cai IEEE Global Conference on Signal and Information Processing . 2014

机译：基于网络的缺血性卒中分析，使用平行的microRNA-mRNA表达谱
5. Genome-wide angiotensin II regulated microRNA expression profiling: A smooth muscle-specific microRNA signature. [D] . Kemp, Jacqueline R. 2013

机译：全基因组的血管紧张素II调节microRNA表达谱：平滑肌特异性microRNA标记。
6. An Integrated Analysis of MicroRNA and mRNA Expression Profiles to Identify RNA Expression Signatures in Lambskin Hair Follicles in Hu Sheep [O] . Xiaoyang Lv, Wei Sun, Jinfeng Yin, -1

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7. An Integrated Analysis of MicroRNA and mRNA Expression Profiles to Identify RNA Expression Signatures in Lambskin Hair Follicles in Hu Sheep. [O] . Xiaoyang Lv, Wei Sun, Jinfeng Yin, 2016

机译：用于鉴定湖羊羔羊毛囊中RNa表达特征的微小RNa和mRNa表达谱的综合分析。

Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients

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