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首页> 外文期刊>Journal of cosmetic and laser therapy >Silicone gel enhances the efficacy of Er:YAG laser treatment for atrophic acne scars: A randomized, split-face, evaluator-blinded, placebo-controlled, comparative trial
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Silicone gel enhances the efficacy of Er:YAG laser treatment for atrophic acne scars: A randomized, split-face, evaluator-blinded, placebo-controlled, comparative trial

机译：硅胶凝胶增强了ER的功效：YAG激光治疗萎缩疤痕：随机，分裂，评估仪 - 盲，安慰剂控制，比较试验

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Background: The effect of topical silicone gel has been studied to prevent scars from burn, postoperative wound and to treat hypertrophic scars. No previous studies have been done to evaluate the efficacy of topical silicone gel on atrophic acne scars. Material and methods: Nineteen patients were treated with three sessions of ablative Er:YAG laser with 1-month intervals. Following each laser treatment, the randomlyassigned silicone gel or placebo was applied in split-face manner. Objective assessments, which included roughness, smoothness, hydration, transepidermal water loss were measured at baseline and prior to each treatment. Subjective assessments by dermatologists and subjects were done at baseline and 1month after last laser treatment. Results: The laser treatments were well tolerated and resulted in clinical improvements. Topical silicone gel treatment resulted in significantly less roughness at weeks 4 and 12 compared with placebo (p0.05). Conclusion: Adding topical silicone gel to ablative Er:YAG laser treatment may provide additional benefits in improving acne scars.
机译：背景：研究了局部硅氧烷凝胶的效果，以防止燃烧，术后伤口和治疗肥厚疤痕的伤疤。已经完成了以前的研究以评估局部硅氧烷凝胶对萎缩痤疮疤痕的功效。材料和方法：十九名患者用三个烧蚀呃：YAG激光进行1个月间隔。在每次激光处理之后，以分裂式方式施加随机assigsed硅氧烷凝胶或安慰剂。目的评估包括粗糙度，平滑，水合，在基线和每次治疗之前测量Transepidermal水分。皮肤科医生和受试者的主观评估在基线和最后一次激光治疗后1个月进行。结果：激光治疗良好耐受，导致临床改进。与安慰剂相比，局部有机硅凝胶处理在第4周和12周内显着较低（P <0.05）。结论：将局部有机硅凝胶添加到消融ER：YAG激光治疗可在改善痤疮疤痕方面提供额外的益处。

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