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首页> 外文期刊>Biotechnology Advances: An International Review Journal >Lipopeptides in microbial infection control: Scope and reality for industry
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Lipopeptides in microbial infection control: Scope and reality for industry

机译：脂肽在微生物感染控制中的应用：行业范围和现实

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摘要

Lipopeptides are compounds that are formed by cyclic or short linear peptides linked with a lipid tail or other lipophilic molecules. Recently, several lipopeptides were characterized, showing surfactant antimicrobial and cytotoxic activities. The properties of lipopeptides may lead to applications in diverse industrial fields including the pharmaceutical industry as conventional antibiotics; the cosmetic industry for dermatological product development due to surfactant and anti-wrinkle properties; in food production acting as emulsifiers in various foodstuffs; and also in the field of biotechnology as biosurfactants. Some lipopeptides have reached a commercial antibiotic status, such as daptomycin, caspofungin, micafungin, and anidulafungin. This will be the focus of this review. Moreover, the review presented here will focus on the biotechnological utilization of lipopeptides in different fields as well as the functional-structure relation, connecting recent aspects of synthesis and structure diversity
机译：脂肽是由与脂质尾巴或其他亲脂性分子连接的环状或短线性肽形成的化合物。最近，表征了几种脂肽，显示出表面活性剂的抗菌和细胞毒性活性。脂肽的特性可能导致其在多种工业领域中的应用，包括制药业中作为常规抗生素的应用;由于表面活性剂和抗皱性能而用于皮肤病学产品开发的化妆品工业;在食品生产中充当各种食品的乳化剂;以及在生物技术领域中作为生物表面活性剂。一些脂肽已达到商业抗生素状态，例如达托霉素，卡泊芬净，米卡芬净和阿尼芬净。这将是这次审查的重点。此外，这里提出的综述将侧重于脂肽在不同领域的生物技术利用以及功能结构关系，将合成和结构多样性的最新方面联系起来

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