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Biotechnological production of muconic acid: current status and future prospects

机译：粘康酸的生物技术生产：现状和未来展望

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Muconic acid (MA), a high value-added bio-product with reactive dicarboxylic groups and conjugated double bonds, has garnered increasing interest owing to its potential applications in the manufacture of new functional resins, bio-plastics, food additives, agrochemicals, and pharmaceuticals. At the very least. MA can be used to produce commercially important bulk chemicals such as adipic acid, terephthalic acid and trimellitic acid. Recently, great progress has been made in the development of biotechnological routes for MA production. This present review provides a comprehensive and systematic overview of recent advances and challenges in biotechnological production of MA. Various biological methods are summarized and compared, and their constraints and possible solutions are also described. Finally, the future prospects are discussed with respect to the current state, challenges, and trends in this field, and the guidelines to develop high-performance microbial cell factories are also proposed for the MA production by systems metabolic engineering
机译：粘康酸（MA）是具有反应性二羧酸基团和共轭双键的高附加值生物产品，由于其在制造新型功能性树脂，生物塑料，食品添加剂，农用化学品和食品中的潜在应用而受到越来越多的关注。药品。至少。 MA可用于生产商业上重要的散装化学品，例如己二酸，对苯二甲酸和偏苯三酸。近来，在MA生产的生物技术路线的开发中已经取得了很大的进展。这篇综述为MA的生物技术生产的最新进展和挑战提供了全面而系统的概述。总结和比较了各种生物学方法，还描述了它们的局限性和可能的​​解决方案。最后，就该领域的现状，挑战和趋势讨论了未来的前景，并且还提出了开发高性能微生物细胞工厂的指南，用于通过系统代谢工程技术生产MA。

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