• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Biotechnology Advances: An International Review Journal >Strategies for enhancing fermentative production of acetoin: a review.
【24h】

Strategies for enhancing fermentative production of acetoin: a review.

机译：增强乙酰丙酮发酵生产的策略：综述。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Acetoin is a volatile compound widely used in foods, cigarettes, cosmetics, detergents, chemical synthesis, plant growth promoters and biological pest controls. It works largely as flavour and fragrance. Since some bacteria were found to be capable of vigorous acetoin biosynthesis from versatile renewable biomass, acetoin, like its reduced form 2,3-butanediol, was also classified as a promising bio-based platform chemical. In spite of several reviews on the biological production of 2,3-butanediol, little has concentrated on acetoin. The two analogous compounds are present in the same acetoin (or 2,3-butanediol) pathway, but their production processes including optimal strains, substrates, derivatives, process controls and product recovery methods are quite different. In this review, the usages of acetoin are reviewed firstly to demonstrate its importance. The biosynthesis pathway and molecular regulation mechanisms are then outlined to depict the principal network of functioning in typical species. A phylogenetic tree is constructed and the relationship between taxonomy and acetoin producing ability is revealed for the first time, which will serve as a useful guide for the screening of competitive acetoin producers. Genetic engineering, medium optimization, and process control are effective strategies to improve productivity as well. Currently, downstream processing is one of the main barriers in efficient and economical industrial acetoin fermentation. The future prospects of microbial acetoin production are discussed in light of the current progress, challenges, and trends in this field.
机译：丙酮是一种挥发性化合物，广泛用于食品，香烟，化妆品，洗涤剂，化学合成，植物生长促进剂和生物害虫防治中。它主要用作香料和香精。由于发现一些细菌能够从通用的可再生生物质中大力合成乙醛素，因此乙醛，如其还原形式的2,3-丁二醇，也被归类为有前途的生物基平台化学品。尽管对2，3-丁二醇的生物生产有一些评论，但很少有人集中在乙酰丙酮上。这两种类似的化合物存在于相同的乙醛酸（或2,3-丁二醇）路径中，但是它们的生产过程（包括最佳菌株，底物，衍生物，过程控制和产物回收方法）却大不相同。在这篇综述中，首先对乙酰丙酮的用法进行了综述，以证明其重要性。然后概述了生物合成途径和分子调控机制，以描绘典型物种的主要功能网络。首次构建了系统进化树，揭示了分类学与乙酰丙酮生产能力之间的关系，这将为筛选竞争性乙酰丙酮生产者提供有用的指导。基因工程，培养基优化和过程控制也是提高生产率的有效策略。当前，下游加工是有效且经济的工业乙酰丙酮发酵的主要障碍之一。根据该领域目前的进展，挑战和趋势，讨论了微生物乙酰丙酮的生产前景。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号