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首页> 外文期刊>Biotechnology Advances: An International Review Journal >Techniques for physicochemical characterization of nanomaterials
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Techniques for physicochemical characterization of nanomaterials

机译：纳米材料的物理化学表征技术

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摘要

Advances in nanotechnology have opened up a new era of diagnosis, prevention and treatment of diseases and traumatic injuries. Nanomaterials, including those with potential for clinical applications, possess novel physicochemical properties that have an impact on their physiological interactions, from the molecular level to the systemic level. There is a lack of standardized methodologies or regulatory protocols for detection or characterization of nanomaterials. This review summarizes the techniques that are commonly used to study the size, shape, surface properties, composition, purity and stability of nanomaterials, along with their advantages and disadvantages. At present there are no FDA guidelines that have been developed specifically for nanomaterial based formulations for diagnostic or therapeutic use. There is an urgent need for standardized protocols and procedures for the characterization of nanoparticles, especially those that are intended for use as theranostics
机译：纳米技术的进步开辟了诊断，预防和治疗疾病和创伤伤害的新时代。纳米材料，包括具有临床应用潜力的纳米材料，具有新颖的物理化学特性，从分子水平到全身水平都对其生理相互作用产生影响。缺乏用于检测或表征纳米材料的标准化方法或管理协议。这篇综述总结了通常用于研究纳米材料的尺寸，形状，表面特性，组成，纯度和稳定性以及其优缺点的技术。目前，还没有专门针对用于诊断或治疗用途的基于纳米材料的制剂开发的FDA指南。迫切需要用于表征纳米颗粒的标准化协议和程序，尤其是那些打算用作治疗学的纳米颗粒

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