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Curcumin, a component of golden spice: From bedside to bench and back

机译:姜黄素,黄金香料的组成部分:从床头到长凳再到背部

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Although the history of the golden spice turmeric (Curcuma longa) goes back thousands of years, it is only within the past century that we learned about the chemistry of its active component, curcumin. More than 6000 articles published within the past two decades have discussed the molecular basis for the antioxidant, anti-inflammatory, antibacterial, antiviral, antifungal, and anticancer activities assigned to this nutraceutical. Over sixty five clinical trials conducted on this molecules, have shed light on the role of curcumin in various chronic conditions, including autoimmune, cardiovascular, neurological, and psychological diseases, as well as diabetes and cancer. The current review provides an overview of the history, chemistry, analogs, and mechanism of action of curcumin
机译:尽管金黄色香料姜黄(Curcuma longa)的历史可以追溯到数千年前,但直到上个世纪我们才了解到其姜黄素活性成分的化学成分。在过去的二十年中发表的6000多篇文章讨论了分配给该营养保健品的抗氧化,抗炎,抗菌,抗病毒,抗真菌和抗癌活性的分子基础。对该分子进行的超过65项临床试验揭示了姜黄素在各种慢性疾病中的作用,包括自身免疫性疾病,心血管疾病,神经疾病,心理疾病以及糖尿病和癌症。当前的评论概述了姜黄素的历史,化学,类似物和作用机理

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