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Giardia/giardiasis - a perspective on diagnostic and analytical tools.

机译:贾第鞭毛虫/贾第鞭毛虫病-诊断和分析工具的观点。

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摘要

Giardiasis is a gastrointestinal disease of humans and other animals caused by species of parasitic protists of the genus Giardia. This disease is transmitted mainly via the faecal-oral route (e.g., in water or food) and is of socioeconomic importance worldwide. The accurate detection and genetic characterisation of the different species and population variants (usually referred to as assemblages and/or sub-assemblages) of Giardia are central to understanding their transmission patterns and host spectra. The present article provides a background on Giardia and giardiasis, and reviews some key techniques employed for the identification and genetic characterisation of Giardia in biological samples, the diagnosis of infection and the analysis of genetic variation within and among species of Giardia. Advances in molecular techniques provide a solid basis for investigating the systematics, population genetics, ecology and epidemiology of Giardia species and genotypes as well as the prevention and control of giardiasis.
机译:贾第鞭毛虫病是由贾第鞭毛虫属的寄生原生生物种引起的人类和其他动物的胃肠道疾病。该疾病主要通过粪便-口途径传播(例如,通过水或食物),在全世界具有重要的社会经济意义。贾第虫的不同物种和种群变异(通常称为集合和/或子集合)的准确检测和遗传特征对于理解其传播模式和宿主光谱至关重要。本文提供了关于贾第鞭毛虫和贾第鞭毛虫病的背景,并综述了一些用于鉴定和鉴定贾第鞭毛虫生物样本中的贾第鞭毛虫的遗传技术,感染的诊断以及贾第鞭毛虫种内和种间遗传变异分析的关键技术。分子技术的进步为研究贾第鞭毛虫属和基因型的系统,种群遗传学,生态学和流行病学以及预防和控制贾第鞭毛虫病奠定了坚实的基础。

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