首页> 外文期刊>Biotechnology Advances: An International Review Journal >Streptokinase - a clinically useful thrombolytic agent [Review]
【24h】

Streptokinase - a clinically useful thrombolytic agent [Review]

机译:链激酶-一种临床上有用的溶栓剂[评论]

获取原文
获取原文并翻译 | 示例
           

摘要

A failure of hemostasis and consequent formation of blood clots in the circulatory system can produce severe outcomes such as stroke and myocardial infraction. Pathological development of blood clots requires clinical intervention with fibrinolytic agents such as urokinase, tissue plasminogen activator and streptokinase. This review deals with streptokinase as a clinically important and cost-effective plasminogen activator. The aspects discussed include: the mode of action; the structure and structure-function relationships; the structural modifications for improving functionality; recombinant streptokinase; microbial production; and recovery of this protein from crude broths.
机译:止血失败并在循环系统中形成血凝块会导致严重后果,例如中风和心肌梗塞。血凝块的病理发展需要临床治疗,包括尿激酶,组织纤溶酶原激活物和链激酶等纤维蛋白溶解剂。这项审查与链激酶作为一种临床上重要且具有成本效益的纤溶酶原激活剂。所讨论的方面包括:作用方式;结构和结构功能关系;为改善功能而进行的结构修改;重组链激酶微生物生产;从粗肉汤中回收这种蛋白质。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号