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首页> 外文期刊>Biotechnology Advances: An International Review Journal >Microbial production of 1,3-propanediol: Recent developments and emerging opportunities
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Microbial production of 1,3-propanediol: Recent developments and emerging opportunities

机译：1,3-丙二醇的微生物生产：最新发展和新机遇

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摘要

1,3-Propanediol, a valuable bifunctional molecule, can be produced from renewable resources using microorganisms. It has several promising properties for many synthetic reactions, particularly for polymer and cosmetic industries. By virtue of being a natural product, relevant biochemical pathways can be harnessed into fermentation processes to produce 1,3-propanediol. Various strategies for the microbial production of 1,3-propanediol are reviewed and compared in this article with their promises and constraints. Furthermore, genetic and metabolic engineering could significantly improve product yields and overcome the limitations of fermentation technology. Present review gives an overview on 1,3-propanediol production by wild and recombinant strains. It also attempts to encompass the various issues concerned in utilization of crude glycerol for 1,3-propanediol production, with particular emphasis laid on biodiesel industries. This review also summarizes the present state of strategies studied for the downstream processing and purification of biologically produced 1,3-propanediol. The future prospect of 1,3-propanediol and its potential as a major bulk chemical are discussed under the light of the current research. [References: 195]
机译：1,3-丙二醇是一种有价值的双功能分子，可以使用微生物从可再生资源中生产。对于许多合成反应，特别是对于聚合物和化妆品工业，它具有几个有希望的特性。由于是天然产物，相关的生化途径可用于发酵过程中以生产1,3-丙二醇。本文对微生物生产1,3-丙二醇的各种策略进行了综述，并对其前景和局限性进行了比较。此外，基因和代谢工程可以显着提高产品产量并克服发酵技术的局限性。目前的评论概述了野生和重组菌株生产1，3-丙二醇。它还试图涵盖与将粗甘油用于1，3-丙二醇生产有关的各种问题，特别是生物柴油行业。这篇综述还总结了目前研究策略的现状，这些策略用于生物生产的1,3-丙二醇的下游加工和纯化。根据当前的研究，讨论了1,3-丙二醇的未来前景及其作为主要散装化学品的潜力。 [参考：195]

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