• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Advances in anatomy embryology and cell biology. >Chapter 4 Degeneration of Select Motor and Limbic Nuclei of the Thalamus in Huntington's Disease (HD)
【24h】

Chapter 4 Degeneration of Select Motor and Limbic Nuclei of the Thalamus in Huntington's Disease (HD)

机译：第四章亨廷顿氏病（HD）中丘脑的选择性运动和边缘核的退化

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Although early neuropathological studies reported degenerative features in subcor-tical brain regions of HD patients (e.g., pallidum, subthalamic nucleus, substantia nigra, claustrum, amygdala) including the thalamus (e.g., global atrophy and volume loss of the thalamus; thalamic astrogliosis; reduced density of microneurons in its cerebellar territory, the ventrolateral nucleus; astrogliosis in the centromedian and parafascicular nuclei; shrinkage of the centromedian nucleus and its nerve cells) (see Chap. 1) (Borrell-Pages et al. 2006; Dom et al. 1976; Finkbeiner and Mitra 2008; Lange and Aulich 1986; Lange et al. 1976; McCaughey 1961; McLardy 1948; Pfeiffer 1913; Terplan 1924; Vonsattel 2008; Vonsattel and DiFiglia 1998; Vonsattel et al. 1985; Walker 2007a, b), the involvement of the thalamus and the extent of its degeneration in HD have been neglected in more recent investigations. Therefore, the affection of the thalamic nuclei is currently not among the established degenerative features of HD.
机译：尽管早期的神经病理学研究报道了HD患者皮层下大脑区域（例如，苍白球，丘脑下核，黑质，锁骨，杏仁核）的变性特征，包括丘脑（例如，丘脑的整体萎缩和体积减少;丘脑星形胶质变性;减少了）小脑区域，腹外侧核中微神经元的密度;着丝粒体和束旁核中的星形胶质变;着丝粒体核及其神经细胞的萎缩（参见第1章）（Borrell-Pages等，2006; Dom等，1976）。 ; Finkbeiner和Mitra 2008; Lange和Aulich 1986; Lange等1976; McCaughey 1961; McLardy 1948; Pfeiffer 1913; Terplan 1924; Vonsattel 2008; Vonsattel和DiFiglia 1998; Vonsattel等人1985; Walker 2007a，b），最近的研究忽略了丘脑的参与及其在HD中的退化程度。因此，丘脑核的影响目前不属于HD既定的退化特征。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号