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Evaluation of Acute Alcohol Intoxication as the Primary Cause of Death: A Diagnostic Challenge for Forensic Pathologists

机译:评价急性酒精中毒作为死亡原因:法医病理学家的诊断挑战

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摘要

Deaths caused by acute alcohol intoxication (AAI) remain a major public health issue. This study is retrospective and descriptive: an 8-year case analysis of deaths due to AAI in Maryland. Study showed that of 150 AAI deaths, the death rate among Hispanics (10.41/100,000 population) was significantly higher than all the non-Hispanics combined (1.88/100,000 population). The majority of individuals were young adults, overweight, and binge drinkers. The obese group showed significantly lower mean heart and peripheral blood alcohol concentration (BAC) (0.36%, 0.37%) than the normal weight group (0.45%, 0.42%). Based on the PBAC and urine AC ratio, 49.6% deaths likely occurred close to peak phase, followed by postabsorptive phase (31.6%) and absorptive phase (18.8%). Our results indicate that forensic pathologists should evaluate postmortem BAC in the light of individual's age, drinking history, body weight, possible phase of alcohol intoxication, and other autopsy findings when certifying AAI as primary cause of death.
机译:急性酒精中毒(AAI)造成的死亡仍然是一个主要的公共卫生问题。本研究是回顾性和描述性的:马里兰州AAI由于AAI而死亡的8年案例分析。研究表明,150岁的死亡人数,西班牙裔(10.41 / 100,000人)的死亡率明显高于所有非西班牙裔(1.88 / 100,000人)。大多数人是年轻的成年人,超重和狂欢饮酒者。肥胖组的平均心脏和外周血醇浓度(BAC)显着低于正常重量基(0.45%,0.42%)。基于PBAC和尿尿毒性比,49.6%可能发生接近峰阶段的死亡,其次是清醒相(31.6%)和吸收相(18.8%)。我们的结果表明,法医病理学家应根据个人年龄,饮酒历史,体重,酒精中毒可能的阶段和其他尸检调查结果评估淘汰的尸体,以及其他尸检调查结果作为死亡的主要原因。

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