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首页> 外文期刊>Journal of glaucoma >Differential Efficacy of Combined Phacoemulsification and Endocyclophotocoagulation in Open-angle Glaucoma Versus Angle-closure Glaucoma
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Differential Efficacy of Combined Phacoemulsification and Endocyclophotocoagulation in Open-angle Glaucoma Versus Angle-closure Glaucoma

机译：联合沉重乳化和环核化学凝固在开放角青光眼与角度闭合青光眼的差异疗效

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Precis: This retrospective study found that combined phacoemulsification and endocyclophotocoagulation reduced intraocular pressure (IOP) to a greater degree in angle-closure glaucoma versus open-angle glaucoma and was effective for all stages of glaucoma. Purpose: Endocyclophotocoagulation (ECP) laser treatment of the ciliary processes is believed to decrease IOP by reducing aqueous production. Anecdotal experience in angle-closure glaucoma suggests that it may also lower IOP by opening the drainage angle to promote aqueous outflow. This study sought to evaluate combined phacoemulsification and ECP (phaco/ECP) in eyes with different types and stages of glaucoma. Patients and Methods: A Retrospective chart review of eyes that underwent phaco/ECP between October 2010 and December 2016 at one institution was conducted. Results: In 63 eyes of 63 patients with an average of 3.0 +/- 1.7 years of follow-up, the 22 eyes with chronic angle-closure glaucoma (CACG) had greater IOP reduction and medication reduction than the 41 eyes with primary open-angle glaucoma at both 1 year (6.4 vs. 2.1 mm Hg, P=0.01; 0.9 vs. 0.2 medications, P=0.04) and final follow-up (6.2 vs. 2.4 mm Hg, P=0.02; 0.9 vs. 0.3 medications, P=0.05). There was no difference in IOP reduction or medication reduction for eyes with mild, moderate, or advanced glaucoma at both 1 year (3.5, 3.9, 0.5 mm Hg, respectively, P=0.18; 0.3, 0.6, 0.4 medications, P=0.58) and final follow-up (3.3, 4.8, 0.7 mm Hg, P=0.11; 0.1, 0.8, 0.4 medications, P=0.14). Conclusions: Eyes with CACG were more responsive to phaco/ECP in terms of IOP and medication reduction compared with eyes with primary open-angle glaucoma. This finding could be partially or entirely due to concurrent cataract extraction and greater CACG preoperative IOP. Phaco/ECP was effective in all stages of glaucoma.
机译：PRECIS：该回顾性研究发现，组合沉乳乳化和环核乳化胶质凝聚，将眼压（IOP）降低到角度闭合青光眼与开口角度荧光眼的更大程度，并且对青光眼的所有阶段有效。目的：通过减少水性生产来降低IOP的睫状菌凝固（ECP）激光治疗。角膜闭合青光眼的轶事经验表明它也可以通过打开排水角来降低IOP以促进水性流出。本研究试图用不同类型和青光眼的阶段评估眼睛眼中的嗜酸术和ECP（Phaco / ECP）。患者和方法：对2010年10月至2016年10月至2016年12月在一个机构进行了展望/ ecp的眼睛的回顾性图表。结果：63只患者平均3.0 +/- 1.7岁的63名患者，22只眼睛具有慢性角度闭合青光眼（CACG）的眼睛较大，减少了比主要开放的41只眼睛两个1年的角度胶罩（6.4与2.1mm Hg，p = 0.01; 0.9 vs.02药物，p = 0.04）和最终随访（6.2对2.4mm Hg，p = 0.02; 0.9和0.3药物，p = 0.05）。 1年（3.5,3.9,0.5mm Hg，P = 0.18分别为轻度，中度或晚期青光眼的眼睛的IOP减少或药物的药物减少或药物减少的差异没有差异最后的随访（3.3,4.8,0.7 mm Hg，p = 0.11; 0.1,0.8,0.4药物，p = 0.14）。结论：与初级开角青光眼的眼睛相比，CACG的眼睛对PHACO / ECP更敏感。这种发现可能是部分或完全是由于同时白内障提取和更大的Cacg术前IOP。 PHACO / ECP在青光眼的所有阶段都有效。

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