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首页> 外文期刊>Journal of glaucoma >Surgical Outcomes of Phacoemulsification Followed by iStent Implantation Versus Goniotomy With the Kahook Dual Blade in Patients With Mild Primary Open-angle Glaucoma With a Minimum of 12-Month Follow-up
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Surgical Outcomes of Phacoemulsification Followed by iStent Implantation Versus Goniotomy With the Kahook Dual Blade in Patients With Mild Primary Open-angle Glaucoma With a Minimum of 12-Month Follow-up

机译：Phacoemumsification的外科蛋解，随后对Khok双叶片的植入植入术治疗患者患者，初级开放角度青光眼患者，至少为12个月的随访

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Purpose: To study surgical outcomes after combined phacoemulsification with either iStent implantation or goniotomy using the Kahook Dual Blade (KDB) with a minimum of 12 months of follow-up. Patients and Methods: Patients with mild primary open-angle glaucoma who underwent phacoemulsification in combination with either iStent implantation or goniotomy using the KDB from 2011 to 2017 were included. Results: In total, 48 eyes in the iStent group and 29 eyes in the KDB group were included with at least 12 months of follow-up. There was no difference in patient age, sex, previous surgery, preoperative or postoperative visual acuity or intraocular pressure (IOP) between the 2 groups. Mean preoperative IOP in the iStent group decreased from 17.6 +/- 4.8 to 15.9 +/- 2.9 mm Hg (P=0.01); mean preoperative IOP in the KDB group decreased from 17.4 +/- 4.3 to 15.0 +/- 4.0 mm Hg (P=0.01). The overall percentage of IOP reduction was 14.3% in the iStent group and 12.6% in the KDB group at 12 months of follow-up. Mean topical glaucoma medication use decreased from 2.0 +/- 0.9 to 0.7 +/- 1.1 in the iStent group and from 2.2 +/- 1.0 to 1.6 +/- 1.3 in the KDB group. Multivariable linear regression accounting for age, sex, race, baseline IOP, and number of eyes treated as covariates indicated a significant reduction in IOP from baseline with both iStent (Wald chi(2)=3.97, P=0.046) and KDB (Wald chi(2)=4.65, P=0.031). Multivariable logistic regression accounting for age, sex, race, baseline IOP, and number of eyes treated as covariates indicated no significant difference in overall success between iStent and KDB (Z-test=0.92, P=0.359). Conclusions: Phacoemulsification in combination with either iStent implantation or goniotomy using the KDB both achieved statistical significant reduction in IOP and number of glaucoma medications at 12 months of follow-up in patients with mild primary open-angle glaucoma with no complications.
机译：目的：使用Khook双叶片（KDB）与不含khook双叶片（Kdb）组合术治疗或甘油膜后，研究手术结果。患者和方法：包括从2011年至2017年使用KDB的术治疗术治疗或使用KDB的植入术或甘油膜术的轻度初级开口荧光眼的患者。结果：总共48只眼内，KDB集团中的29只眼睛都包含至少12个月的随访。患者年龄，性别，先前手术，术前或术后视力或术后视力或眼内压（IOP）没有差异。 Istent组的平均术前IOP从17.6 +/- 4.8降至15.9 +/- 2.9 mm hg（p = 0.01）; KDB组中的平均术前IOP从17.4 +/- 4.3降至15.0 +/- 4.0 mm Hg（P = 0.01）。 IOP减少的总体百分比为14.3％，在后续12个月的KDB组中，12.6％。平均局部青光眼药物使用在ISTENT组中的2.0 +/- 0.9至0.7 +/- 1.1中减少，在KDB组中的2.2 +/- 1.0至1.6 +/- 1.3。年龄，性别，种族，基线IOP和作为协变量的眼睛数量的多变量线性回归核算表明，来自基线的IOP显着减少了（Wald Chi（2）= 3.97，P = 0.046）和KDB（Wald Chi （2）= 4.65，P = 0.031）。年龄，性别，种族，基线IOP和被视为可协变量的眼睛数量的多变量逻辑回归核算表明，ISTENT和KDB之间的总体成功没有显着差异（Z-Test = 0.92，P = 0.359）。结论：使用KDB与不含KDB的植入或甘油膜组合的Phacoem乳化在不良机初级开角青光眼患者的12个月内达到IOP和青光眼药物数量的统计显着降低。

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