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首页> 外文期刊>Digestive diseases >STW 5 (Iberogast) Therapy in Gastrointestinal Functional Disorders
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STW 5 (Iberogast) Therapy in Gastrointestinal Functional Disorders

机译：STW 5（Ibrogast）胃肠功能障碍治疗

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Background: Functional gastrointestinal disorders (FGIDs) are very common and affect populations worldwide. A majority of patients are affected by a variety of heterogenous gastrointestinal symptoms (GIS) related to the upper and lower digestive system with frequent overlap and mostly of mild to moderate degree. The herbal medicinal preparation STW 5 is documented as an effective therapeutic option for treating FGID. Studies Conducted in Summary: STW 5 has been in use for more than 50 years in clinical practice and proven to be effective and safe in the management of FGID. The high efficacy of STW 5 on symptoms clustered in functional dyspepsia (FD) and irritable bowel syndrome (IBS) as well as on individual abdominal symptoms is demonstrated in 5 controlled, randomized double-blind studies in FD and in one trial conducted in patients with IBS. In addition the beneficial therapeutic effect of STW 5 on FGD as well as safety issues have been reported in a series of non interventional studies conducted in several thousands of adult patients and including 980 children. An additional study has been performed addressing the question as to how quickly the therapeutic effect is obtained after STW 5 administration. Key Messages from These Studies: STW 5 is an effective phyto-medication for treating patients with FD and IBS. STW 5 acts beneficially on abdominal symptom clusters as well as on individual GIS in adults and children. The time to onset of action is rapid, well tolerated and safe. The repetitive use of STW 5 is an appropriate option in clinical practice for patients with FGID. (C) 2018 The Author(s)
机译：背景：功能性胃肠疾病（FGID）非常普遍，影响全世界人口。大多数患者受到与上层和下消化系统有关的各种异源性胃肠道症状（GIS）的影响，频繁重叠，主要是轻度至中度程度。草药制剂STW 5被记录为治疗FGID的有效治疗选择。总结中进行的研究：STW 5已在临床实践中已使用超过50年，并经过验证在尿道管理方面有效和安全。 STW 5对功能性消化不良（FD）和肠胃肠综合征（IBS）组聚集的症状的高疗效以及各个腹部症状，在FD和患者进行的一项试验中进行了5种受控，随机的双盲研究肠易激综合症。此外，STW 5对FGD以及安全问题的有益治疗效果在几千名成千上万的成年患者和980名儿童中进行了一系列的非介入研究。已经进行了额外的研究，以解决迄今为止在STW 5给药后获得的治疗效果的速度。来自这些研究的关键消息：STW 5是治疗FD和IBS患者的有效植物药物。 STW 5有利地作用于腹部症状簇以及成人和儿童的个体GIS。开始行动的时间是快速，耐受性和安全的。 The repetitive use of STW 5 is an appropriate option in clinical practice for patients with FGID. （c）2018提交人

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