...
首页> 外文期刊>Journal of industrial and engineering chemistry >Size-controlled synthesis, characterization, and cytotoxicity study of monodisperse poly(dimethylsiloxane) nanoparticles
【24h】

Size-controlled synthesis, characterization, and cytotoxicity study of monodisperse poly(dimethylsiloxane) nanoparticles

机译:单分散聚(二甲基硅氧烷)纳米颗粒的尺寸控制合成,表征和细胞毒性研究

获取原文
获取原文并翻译 | 示例
           

摘要

Polydimethylsiloxane (PDMS) nanoparticles (NPs) were synthesized using dimethylsiloxane and tetraethyl orthosilicate as precursors via a modified Stober process. A diluted ammonia solution was added to the reaction mixture. This induced base-catalyzed hydrolysis and condensation, forming dispersed nanocolloids. The as -synthesized organosilica NPs exhibited excellent colloidal stability without any noticeable precipitation in water. The particle size was readily tunable, in a diameter range of approximately 50-300 nm, by changing the amount of catalysts added to the reaction. Furthermore, we evaluated the cytotoxicity of PDMS NPs using a CCK-8 assay to demonstrate that PDMS NPs are promising for biomedical applications. (C) 2017 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
机译:使用二甲基硅氧烷和硅氧烷作为前体通过改性的阶级方法合成聚二甲基硅氧烷(NPS)。 将稀释的氨溶液加入到反应混合物中。 这种诱导的碱催化水解和缩合,形成分散的纳米细胞。 作为-Synthesized的有机菌NPS表现出优异的胶体稳定性,而没有任何显着的沉淀。 通过改变加入到反应中的催化剂的量,粒度在大约50-300nm的直径范围内易于调谐。 此外,我们使用CCK-8测定评估了PDMS NP的细胞毒性,以证明PDMS NPS对生物医学应用是有望的。 (c)2017年韩国工程和工程化学学会。 elsevier b.v出版。保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号