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Bionanoconjugate-Based Composites for Decontamination of Nerve Agents

机译:用于生物活性剂去污的基于Bionanoconjugate的复合材料

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We have developed enzyme-based composites that rapidly and effectively detoxify simulants of V- and G-type chemical warfare nerve agents. The approach was based on the efficient immobilization of organophosphorus hydrolase onto carbon nanotubes to form active and stable conjugates that were easily entrapped in commercially available paints. The resulting catalytic-based composites showed no enzyme leaching and rendered >99% decontamination of 10 g/m~2 paraoxon, a simulant of the V-type nerve agent, in 30 minutes and >95% decontamination of diisopropylfluorophosphate, a simulant of G-type nerve agent, in 45 minutes. The formulations are expected to be environmentally friendly and. to offer an easy to use, on demand, decontamination alternative to chemical approaches for sustainable material self-decontamination.
机译:我们开发了基于酶的复合材料,可快速有效地对V型和G型化学战神经毒剂的模拟物进行解毒。该方法基于将有机磷水解酶有效地固定在碳纳米管上,以形成易于捕获在市售涂料中的活性和稳定共轭物。所得的基于催化的复合材料在30分钟内无酶浸出,并且在30分钟内对10 g / m〜2对氧磷(V型神经毒剂的模拟物)进行了> 99%的去污,对二异丙基氟磷酸盐(对G的模拟物)进行了95%的去污。型神经毒剂,需45分钟。预期该制剂是环境友好的。提供按需使用,易于使用的去污替代品,以化学方法实现可持续的材料自去污。

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