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首页> 外文期刊>Journal of investigative surgery: The official journal of the Academy of Surgical Research >Minimally Invasive Plating Osteosynthesis in the Treatment of Humeral Shaft Fractures: A Meta-Analysis
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Minimally Invasive Plating Osteosynthesis in the Treatment of Humeral Shaft Fractures: A Meta-Analysis

机译：肱骨轴骨折治疗中的微创镀骨合成：Meta分析

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Background: Whether minimally invasive plating osteosynthesis (MIPO) or other operative interventions is superior in the treatment of humeral shaft fractures remains controversial. Therefore, we conducted a meta-analysis to quantitatively compare the clinical outcomes of MIPO and other operative interventions in the treatment of humeral shaft fractures. Methods: Pubmed, Embase, and Web of Science were systematically searched to identify all available studies comparing clinical outcomes between patients receiving MIPO and other operative interventions. The weight mean difference (WMD) was pooled to compare the operative time, union time, University of California, Los Angeles (UCLA) score, and Mayo elbow performance index (MEPI).The risk ratio (RR) was pooled to compare the union rate, and incidence of complications. Pooled estimates were calculated by using a fixed-effects model or a randomized-effects model, according to the heterogeneity among studies. Results: Nine studies were included in this meta-analysis. Our results suggest that both MIPO and other operative interventions can achieve similar union time, UCLA score, MEPI, and union rate. However, MIPO is associated with better outcomes including shorter operation time, and lower incidence of radial nerve injury. Conclusion: Evidence from this meta-analysis demonstrated that, MIPO is effective but safer than other operative interventions in the treatment of humeral shaft fracture. However, due to the potential limitations in this meta-analysis, randomized controlled trials with larger sample sizes using appropriate blinding methods are needed to confirm these findings.
机译：背景：无论是微创镀层骨合成（MIPO）或其他操作干预在肱骨轴骨折的治疗中是否优于争议。因此，我们进行了荟萃分析，以定量地比较MIPO和其他手术干预的临床结果，治疗肱骨轴骨折。方法：系统地搜索PubMed，Embase和Science Web，以识别所有可用的研究，比较接受MIPO和其他手术干预患者患者的临床结果。合并重量平均差异（WMD）以比较操作时间，加利福尼亚大学，洛杉矶（UCLA）得分和Mayo肘部性能指数（MEPI）。汇集了风险比（RR）以比较联盟率和并发症发病率。根据研究中的异质性，通过使用固定效果模型或随机效果模型计算汇总估计。结果：该荟萃分析中包括9项研究。我们的结果表明，MIPO和其他操作干预措施都可以实现类似的联盟时间，UCLA得分，MEPI和联盟率。然而，MIPO与更好的结果相关，包括较短的操作时间和桡神经损伤的发病率降低。结论：来自该元分析的证据证明，MIPO是有效的，但比其他操作干预措施的治疗肱骨轴骨折。然而，由于该荟萃分析中的潜在限制，需要使用适当的致盲方法具有较大样本尺寸的随机对照试验来确认这些发现。

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