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Development of a TB-PCR Kit for the Diagnosis of Tuberculosis

机译：用于结核病诊断的TB-PCR试剂盒的开发

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More people die of tuberculosis (TB) in India than due to any other infectious disease. The early diagnosis of pulmonary TB (PTB) and extra-pulmonary TB (EPTB) is the most important step that will help in controlling the transmission of TB in the community. As the conventional techniques lack sensitivity, specificity or are too lengthy, it is important to develop a test which is rapid, sensitive and specific. A test based on polymerase chain reaction (PCR) fulfills all these criteria and hence a PCR test was developed at RMC for the rapid diagnosis of tuberculosis. After successful validation of the test, both in PTB and EPTB, and development of an efficient DNA extraction method, a diagnostic kit was developed in collaboration with JONAKI, BRIT. The kit, now launched in the market, will be useful in early diagnosis of TB.
机译：在印度死于结核病的人数比任何其他传染病都要多。肺结核（PTB）和肺外结核（EPTB）的早期诊断是最重要的步骤，将有助于控制社区中结核病的传播。由于常规技术缺乏敏感性，特异性或太长，因此开发一种快速，灵敏和特异的测试非常重要。基于聚合酶链反应（PCR）的测试可满足所有这些标准，因此RMC开发了一项PCR测试来快速诊断结核病。成功验证了PTB和EPTB的测试结果并开发出有效的DNA提取方法后，与JONAKI，BRIT合作开发了诊断试剂盒。该试剂盒现已投放市场，将对结核病的早期诊断有用。

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