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首页> 外文期刊>Acta academiae agriculturae ac technicae olstenensis:veterinaria >THE INFLUENCE OF ELEVATED OZONE CONCENTRATION IN AIR ON SELECTED BIOCHEMICAL PARAMETERS, HEMATOLOGICAL INDICES AND IMMUNOLOGICAL PARAMETERS IN RATS FED WITH VARIOUS VITAMIN E AND C CONCENTRATIONS: III. The influence of elevated ozone concentration in
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THE INFLUENCE OF ELEVATED OZONE CONCENTRATION IN AIR ON SELECTED BIOCHEMICAL PARAMETERS, HEMATOLOGICAL INDICES AND IMMUNOLOGICAL PARAMETERS IN RATS FED WITH VARIOUS VITAMIN E AND C CONCENTRATIONS: III. The influence of elevated ozone concentration in

机译:空气中臭氧浓度升高对不同维生素E和C喂养的大鼠所选生化参数,血液学指标和免疫学参数的影响:III。臭氧浓度升高的影响

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摘要

Three separate experiments (E, E+C and C) were carried out on 180 Wistar/Hannower rats. The rats were divided into six groups in each experiment depending on their exposure and the vitamin E and C supplement in the standard feed. The control animalsand the rats from group II were fed the standard "Murigran" feed for rodents, but animals in groups III-VI received feed enriched with vitamin E, E+C or C, The experimental animals from groups II -VI were exposed to 1.0+0.4 mg O_3/m~3 air for 8 hours a day over 5 weeks After the experiment, the rat blood was taken and the principal hematological indices, G-6-PD activity as well as the concentrations of protein, thiol groups and α-tocopherol in the red blood cells were determined. The results were statistically analysed. The negative ozone influence on the red blood cell system was observed. Based on the experiments, it may be concluded that feeding animals with the feed supplemented with vitamins E and C is beneficial to rats when exposed to air withelevated ozone concentrations.
机译:在180只Wistar / Hannower大鼠上进行了三个单独的实验(E,E + C和C)。根据它们的暴露量以及标准饲料中的维生素E和C补充剂,在每个实验中将大鼠分为六组。对照动物和来自第二组的大鼠饲喂啮齿动物标准的“ Murigran”饲料,但是第三至第六组的动物接受富含维生素E,E + C或C的饲料。在5周内每天1.0 +0.4 mg O_3 / m〜3空气,持续8小时实验后,抽取大鼠血液,并采集其主要血液学指标,G-6-PD活性以及蛋白质,硫醇基和测定了红细胞中的α-生育酚。对结果进行统计学分析。观察到臭氧对红细胞系统的负面影响。基于实验,可以得出结论,当动物暴露于空气中臭氧浓度升高的情况下,用补充了维生素E和C的饲料喂养动物对大鼠有益。

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