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首页> 外文期刊>Journal of magnetic resonance imaging: JMRI >Can Resting-State Functional MRI Serve as a Complement to Task-Based Mapping of Sensorimotor Function? A Test-Retest Reliability Study in Healthy Volunteers
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Can Resting-State Functional MRI Serve as a Complement to Task-Based Mapping of Sensorimotor Function? A Test-Retest Reliability Study in Healthy Volunteers

机译：休息状态的功能MRI可以作为SensoRImotor函数的基于任务的映射补充？ 健康志愿者中的测试 - 重新测试可靠性研究

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Purpose: To investigate if res ting-state functional MRI (fMRI) reliably can serve as a complement to task-based fMRI for presurgical mapping of the sensorimotor cortex. Materials and Methods: Functional data were obtained in 10 healthy volunteers using a 3 Tesla MRI system. Each subject performed five bilateral finger tapping experiments interleaved with five resting-state experiments. Following preprocessing, data from eight volunteers were further analyzed with the general linear model (finger tapping data) and independent component analysis (rest data). Test-retest reliability estimates (hit rate and false alarm rate) for resting-state fMRI activation of the sensorimotor network were compared with the reliability estimates for task-evoked activation of the sensorimotor cortex. The reliability estimates constituted a receiver operating characteristics curve from which the area under the curve (AUC) was calculated. Statistical testing was performed to compare the two groups with respect to reliability. Results: The AUC was generally higher for the task experiments, although median AUC was not significantly different on a group level. Also, the two groups showed comparable levels of within-group variance. Conclusion: Test-retest reliability was comparable between resting-state measurements and task-based fMRI, suggesting that presurgical mapping of functional networks can be a supplement to task-based fMRI in cases where patient status excludes task-based fMRI.
机译：目的：研究RES TING状态功能MRI（FMRI）可靠地可以作为对SENSOSIMOTOR皮质的前型映射的基于任务的FMRI补充。材料和方法：使用3特斯拉MRI系统在10个健康志愿者中获得功能数据。每个受试者进行五个双侧手指攻丝实验，用五个休息状态进行了交错。在预处理之后，通过通用线性模型（手指攻丝数据）和独立分量分析（REST数据）进一步分析来自八个志愿者的数据。与SensoRIMOTOR网络的休息状态FMRI激活的测试 - RETEST可靠性估计（命中率和误报率）与SensoRIMOTOR皮质的任务诱发激活的可靠性估计进行了比较。可靠性估计构成了一种接收器操作特性，计算曲线（AUC）下的区域的曲线。进行统计测试以比较两组相对于可靠性。结果：任务实验通常较高，但在群体水平上中位AUC没有显着差异。此外，两组在组内差异的相当水平。结论：测试 - 保持性可靠性与基于休息状态测量和任务的FMRI之间的相当可比，这表明功能网络的预设映射可以是基于任务的FMRI的补充，其中患者状态不包括基于任务的FMRI。

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