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首页> 外文期刊>Journal of Medical Virology >Case Report: Risk of virus infection after accidental blood inoculation from a multi-infected AIDS patient
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Case Report: Risk of virus infection after accidental blood inoculation from a multi-infected AIDS patient

机译：案例报告：从多感染艾滋病患者中发生意外血液后病毒感染风险

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摘要

Infections caused by blood-borne viruses such as hepatitis B and C and the human immunodeficiency virus (HIV) are associated commonly with needlestick injuries, especially in a hospital setting. A prospective investigation was conducted on a medical doctor who suffered an accidental needlestick injury during blood collection from a patient with AIDS. The patient's blood contained 195,000 copies of HIV RNA, 1×10 6 IU hepatitis C virus (HCV) RNA, and 10 7 copies of parvovirus B19 DNA per 1ml plasma. It was positive for cytomegalovirus virus and evidence of a resolved hepatitis B virus (HBV) infection was found. HCV viremia was detected in the physician 15 days later and was not resolved by seroconversion after 57 days. HIV infection was not transmitted, possibly because of the immediate use of anti-HIV prophylactic drugs after exposure. Parvovirus B19 infection was presumably prevented by pre-existing specific antibodies in the patient. Considering that many HIV carriers are coinfected with hepatitis B and C viruses, this case report support the knowledge that the risk of HCV transmission from a patient with AIDS is greater than that of HIV.
机译：由肝炎病毒如乙型肝炎和C和人类免疫缺陷病毒（HIV）引起的感染通常与针刺损伤有关，特别是在医院环境中。在从艾滋病患者的患者血液收集期间遭受意外针刺损伤的医生进行了一项预期调查。患者的血液含有195,000份HIV RNA，1×10 6 IU丙型肝炎病毒（HCV）RNA，和GT;每1ml等离子体10 7个Parvovirus B19 DNA拷贝。对于巨细胞病毒病毒和分辨的乙型肝炎病毒（HBV）感染的证据是阳性的。在5天后在医生中检测到HCV病毒血症，并且在57天后没有通过SEROCONVersvers解决。艾滋病毒感染未经传播，可能是因为暴露后立即使用抗HIV预防药物。可能通过患者预先存在的特异性抗体预防细胞病毒B19感染。考虑到许多艾滋病毒携带者用乙型肝炎和C病毒繁殖，本案例报告支持知识，即HCV从患者与艾滋病患者的风险大于艾滋病毒的风险。

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