• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Biotechnology Progress >Quantitative Determination of Glucose Transfer Between Cocurrent Laminar Water Streams in a H-Shaped MicroChannel
【24h】

Quantitative Determination of Glucose Transfer Between Cocurrent Laminar Water Streams in a H-Shaped MicroChannel

机译：H型微通道中并流层流之间的葡萄糖转移的定量测定

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

To explore the applicability of a laminar fluid diffusion interface (LFDI) for the controlled feeding of microbioreactors, glucose diffusion experiments were carried out in a rounded H-shaped microstructure etched in a glass substrate. The diffusion channel of the microstruc-ture had a length of 4 mm and a depth of 50 μm with a trapezoidal cross section with a width of 100 μm at the bottom and 200 μm at the surface of the channel. The microchannel was operated at residence times of less than 1 s ensuring high-mass-transfer rates. It was confirmed, both by microscopic observations as well as computational fluid dynamics (CFD) studies that the flow characteristics in the microchannel were fully laminar. Special attention was paid to flow splitting at the end of the channel, because the CFD simulations indicated that the performance of the device was sensitive to unequal flow splitting. The difference in outflow volume of the two streams was measured to be small (1.25% ± 0.6%). The measured glucose concentration in both exit ports at a fixed residence time was found to be stable in time and reproducible in multiple experiments. CFD simulation was shown to be a powerful tool for estimating the mass transfer in the LFDI, even at very short residence times. The results obtained in this work show the applicability of LFDI for the controlled diffusive supply of a solute to a water stream, with as possible application substrate and/or precursor feeding to microreactors.
机译：为了探索层流扩散界面（LFDI）在控制微生物进料中的适用性，在玻璃基板上蚀刻的圆形H形微结构中进行了葡萄糖扩散实验。所述微结构的扩散通道的长度为4mm，深度为50μm，具有梯形横截面，其底部的宽度为100μm，而其表面的宽度为200μm。微通道的停留时间少于1秒，可确保高质量传输速率。通过显微镜观察和计算流体力学（CFD）研究都证实，微通道中的流动特性是完全层流的。特别要注意通道末端的分流，因为CFD模拟表明设备的性能对不均等的分流很敏感。测得两条流的流出量之差很小（1.25％±0.6％）。发现在固定停留时间在两个出口处测得的葡萄糖浓度在时间上是稳定的并且在多个实验中可再现。 CFD模拟被证明是即使在很短的停留时间下也可以估算LFDI中的传质的有力工具。在这项工作中获得的结果表明，LFDI适用于控制溶质向水流的扩散扩散供应，并尽可能将应用底物和/或前体供入微反应器。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号