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首页> 外文期刊>Journal of Materials Chemistry, B. materials for biology and medicine >Progress in the therapeutic applications of polymer-decorated black phosphorus and black phosphorus analog nanomaterials in biomedicine
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Progress in the therapeutic applications of polymer-decorated black phosphorus and black phosphorus analog nanomaterials in biomedicine

机译：聚合物装饰黑色磷和黑磷含量纳米材料在生物医学中的治疗应用进展

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摘要

Wonderful black phosphorus (BP) and some BP analogs (BPAs) have been increasingly studied for their biomedical applications owing to their fascinating properties and biodegradability, but opportunities and challenges have always coexisted in their study. Poor stability upon exposure to the natural environment is the major obstacle hampering theirin vivoapplications. BP/polymer and BPAs/polymer nanocomposites can not only efficiently prevent their oxidation and aggregation but also exhibit "biological activity" due to synergistic effects. In this review, we briefly describe the synthesis methods and stability strategies of BP/polymer and BPAs/polymer. Then, advances pertaining to their exciting therapeutic applications in various fields are systematically introduced, such as cancer therapy (phototherapy, drug delivery, and synergistic immunotherapy), bone regeneration, and neurogenesis. Some challenges for future clinical trials and possible directions for further study are finally discussed.
机译：由于其迷人的性能和生物降解性，越来越多的黑磷（BP）和一些BP类似物（BPA）越来越多地研究了他们的生物医学应用，但在他们的研究中，机会和挑战总是共存。暴露于自然环境时稳定性较差是妨碍他们的体育活动的主要障碍。 BP /聚合物和BPA /聚合物纳米复合材料不仅可以有效地防止它们的氧化和聚集，而且还具有由于协同效应而表现出“生物活性”。在本文中，我们简要介绍了BP /聚合物和BPA /聚合物的合成方法和稳定性策略。然后，系统地引入了各种领域的激发治疗应用的进展，例如癌症治疗（光疗，药物递送和协同免疫疗法），骨再生和神经发生。终于讨论了未来临床试验的一些挑战和进一步研究的可能指示。

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    An Dong; Fu Jianye; Xie Zhongjian; Xing Chenyang; Zhang Bin; Wang Bing; Qiu Meng;

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    Shenzhen Univ Inst Microscale Optoelect Int Collaborat Lab 2D Mat Optoelect Sci &

    Technol Minist Educ Shenzhen 518060 Peoples R China;

    Shenzhen Univ Inst Microscale Optoelect Int Collaborat Lab 2D Mat Optoelect Sci &

    Technol Minist Educ Shenzhen 518060 Peoples R China;

    Shenzhen Int Inst Biomed Res Shenzhen 518116 Peoples R China;

    Shenzhen Univ Inst Microscale Optoelect Int Collaborat Lab 2D Mat Optoelect Sci &

    Technol Minist Educ Shenzhen 518060 Peoples R China;

    Shenzhen Univ Inst Microscale Optoelect Int Collaborat Lab 2D Mat Optoelect Sci &

    Technol Minist Educ Shenzhen 518060 Peoples R China;

    Shenzhen Univ Inst Microscale Optoelect Int Collaborat Lab 2D Mat Optoelect Sci &

    Technol Minist Educ Shenzhen 518060 Peoples R China;

    Ocean Univ China Minist Educ Key Lab Marine Chem Theory &

    Technol Qingdao 266100 Peoples R China;

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  • 正文语种 eng
  • 中图分类 分析化学;
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