Native versus deglycosylated IgM in anti-MAG neuropathy: Correlation with clinical status - Study of 10 cases

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Native versus deglycosylated IgM in anti-MAG neuropathy: Correlation with clinical status - Study of 10 cases

机译：抗MAG神经病的本地与脱糖基状的IgM：与临床状态相关 - 研究10例

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Background/purpose: In anti-myelin associated glycoprotein (anti-MAG) neuropathies, there is evidence that anti-MAG antibodies are pathogenic but numerous studies report the absence or a weak correlation between the titers of these antibodies and disease course. In this study we assessed the relationships between MAG and glycosylated moieties located on Fc fragment of IgM anti-MAG.

机译：背景/目的：在抗髓鞘相关糖蛋白（抗MAG）神经病中，有证据表明抗MAG抗体是致病的，但许多研究报告了这些抗体和疾病过程的滴度之间的缺失或弱相关性。在这项研究中，我们评估了位于IgM抗MAG的Fc片段的Mag和糖基化部分之间的关系。

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《Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology》 |2020年第2020期|共10页
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正文语种 eng
中图分类神经病学;
关键词
Anti-MAG neuropathy; Deglycosylation; IgM; Fc fragment;

机译：抗MAG神经病变;脱糖基化;IgM;Fc片段;

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专利

1. Native versus deglycosylated IgM in anti-MAG neuropathy: Correlation with clinical status - Study of 10 cases [J] . Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology . 2020,第期

机译：抗MAG神经病的本地与脱糖基状的IgM：与临床状态相关 - 研究10例
2. Obinutuzumab, a potent anti–B-cell agent, for rituximab-unresponsive IgM anti-MAG neuropathy [J] . Goran Rakocevic, Ubaldo Martinez-Outschoorn, Marinos C. Dalakas Neurology - Neuroimmunology Neuroinflammation . 2018,第4期

机译：奥比妥珠单抗，一种有效的抗B细胞药物，用于利妥昔单抗无反应的IgM抗MAG神经病
3. High prevalence of the MYD88 L265P mutation in IgM anti-MAG paraprotein-associated peripheral neuropathy [J] . Vos Josephine Mathilde, Notermans Nicolette C., DSa Shirley, Journal of Neurology, Neurosurgery and Psychiatry . 2018,第9期

机译：IGM抗MAG帕拉普蛋白相关周围神经病变高88 L265P突变的高患病率
4. Native ATM versus IP over ATM: comparative study [C] . Chahed, T., Ben Fredj, . 1999

机译：本地ATM与IP over ATM：比较研究
5. A Correlational Quantitative Study on the Relationship of a Clinical Instructor's Emotional Intelligence to the Degree of Student Satisfaction with the Clinical Instructor [D] . Rudolph, Michelle M. 2017

机译：临床指导员情绪智力与学生满意度之间的相关定量研究
6. Obinutuzumab a potent anti–B-cell agent for rituximab-unresponsive IgM anti-MAG neuropathy [O] . Goran Rakocevic, Ubaldo Martinez-Outschoorn, Marinos C. Dalakas 2018

机译：奥比妥珠单抗一种有效的抗B细胞药物用于利妥昔单抗无反应的IgM抗MAG神经病
7. Neuropathies périphériques et hémopathies B : de l'étude clinique des neuropathies associées à une gammapathie monoclonale IgM à activité anti-MAG au mécanisme de mort cellulaire induit par le Fingolimod (FTY720) dans les hémopathies B [O] . Delmont Émilien 2013

机译：周围神经病变和血肿B：来自与具有抗MAG活性且由芬戈莫德（FTY720）引起的细胞死亡机制的IgM单克隆抗丙种球蛋白病相关的神经病的临床研究

Native versus deglycosylated IgM in anti-MAG neuropathy: Correlation with clinical status - Study of 10 cases

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