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首页> 外文期刊>Journal of Micromechanics and Microengineering >Single-channel opto-neurostimulators: a review
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Single-channel opto-neurostimulators: a review

机译：单通道光学神经刺激剂：审查

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Optogenetics is a revolutionary neuromodulation technique to excite or inhibit the activity of the targeted neurons that express light-sensitive opsin proteins. Opto-neurostimulators as neural interface devices are significantly important for optogenetic applications in neuroscience and future clinical research. To date, a wide variety of optical stimulators have been developed and could be classified into two broad categories: single-channel and multi-channel stimulators. Although multi-channel opto-neurostimulators allow spatially controlled optical stimulation of cells, they require complicated fabrication procedures and might require specialized coupling strategies at the distal end of the optical source. As an alternative, single-channel opto-neurostimulators are gradually being prevalent in many applications for their simplicity, ease of use, and low cost. We have reviewed a variety of single-channel optogenetic neural stimulators that were developed in recent years, based on different light sources, material selection, and tethered or wireless systems. This paper accumulates and summarizes these single-channel opto-neurostimulators to provide a comprehensive outlook for the trend of this field.
机译：邻光学是一种革命性的神经调节技术，可激发或抑制表达光敏Opsin蛋白的靶神经元的活性。作为神经界面器件的光学神经刺激剂对于神经科学和未来临床研究的致光学应用显着重要。迄今为止，已经开发了各种光学刺激器，可以分为两种广泛类别：单通道和多通道刺激器。虽然多通道光神经刺激剂允许空间控制的电池光学刺激，但它们需要复杂的制造程序，并且可能在光源的远端处需要专门的耦合策略。作为替代方案，单通道光学神经刺激剂在许多应用中逐渐普遍，用于其简单性，易用性和低成本。我们已审查了各种单通道的光素神经刺激器，近年来基于不同的光源，材料选择和系列或无线系统。本文积累并总结了这些单通道光神经刺激者，为该领域的趋势提供了全面的展望。

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