Polyethylene glycol (PEG) and other bioactive solutions with neurorrhaphy for rapid and dramatic repair of peripheral nerve lesions by PEG-fusion

Ghergherehchi Cameron L.; Mikesh Michelle; Sengelaub Dale R.; Jackson David M.; Smith Tyler; Nguyen Jacklyn; Shores Jaimie T.; Bittner George D.

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Polyethylene glycol (PEG) and other bioactive solutions with neurorrhaphy for rapid and dramatic repair of peripheral nerve lesions by PEG-fusion

机译：聚乙二醇（PEG）和其他生物活性溶液，具有神经栓塞的厚度和剧烈修复PEG融合

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Background: Nervous system injuries in mammals often involve transection or segmental loss of peripheral nerves. Such injuries result in functional (behavioral) deficits poorly restored by naturally occurring 1-2 mm/d axonal outgrowths aided by primary repair or reconstruction. "Neurorrhaphy" or nerve repair joins severed connective tissues, but not severed cytoplasmic/plasmalemmal extensions (axons) within the tissue.

机译：背景：哺乳动物的神经系统损伤往往涉及过期或周围神经的细分丧失。这种损伤导致功能性（行为）缺陷，通过自然发生的1-2 mm / d轴突差异，通过主要修复或重建辅助。 “神经腐败”或神经修复加入切断的结缔组织，但未在组织内切断细胞质/ plasmalmal延伸（轴突）。

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来源
《Journal of Neuroscience Methods》 |2019年第2019期|共12页
作者
Ghergherehchi Cameron L.; Mikesh Michelle; Sengelaub Dale R.; Jackson David M.; Smith Tyler; Nguyen Jacklyn; Shores Jaimie T.; Bittner George D.;
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作者单位

Univ Texas Dept Mol Biosci Austin TX 78712 USA;

Univ Texas Dept Neurosci Austin TX 78712 USA;

Indiana Univ Dept Psychol &

Brain Sci Bloomington IN 47405 USA;

Neurapt Therapeut Lafayette CO USA;

Univ Texas Dept Mol Biosci Austin TX 78712 USA;

Univ Texas Dept Neurosci Austin TX 78712 USA;

Johns Hopkins Univ Sch Med VCA Lab Dept Plast &

Reconstruct Surg Ross Res Bldg 749D 720 Rutland;

Univ Texas Dept Neurosci Austin TX 78712 USA;

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原文格式 PDF
正文语种 eng
中图分类人体生理学;
关键词
Polyethylene glycol fusion; Peripheral nerve injury; Rat sciatic nerve repair; Wallerian degeneration; Neuromuscular junction re-innervation; Allograft; Neurorrhaphy;

机译：聚乙二醇融合;周围神经损伤;大鼠坐骨神经修复;Wallerian变性;神经肌肉结重新分析;同种异体移植;神经腐败;

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1. Polyethylene glycol (PEG) and other bioactive solutions with neurorrhaphy for rapid and dramatic repair of peripheral nerve lesions by PEG-fusion [J] . Ghergherehchi Cameron L., Mikesh Michelle, Sengelaub Dale R., Journal of Neuroscience Methods . 2019,第期

机译：聚乙二醇（PEG）和其他生物活性溶液，具有神经栓塞的厚度和剧烈修复PEG融合
2. End-to-side neurorrhaphy repairs peripheral nerve injury: sensory nerve induces motor nerve regeneration [J] . Qing Yu, She-hong Zhang, Tao Wang, 中国神经再生研究（英文版） . 2017,第010期

机译：端到端神经性腹泻修复周围神经损伤：感觉神经诱导运动神经再生
3. Polyethylene Glycol Fusion Repair Prevents Reinnervation Accuracy in Rat Peripheral Nerve [J] . Robinson Grant A., Madison Roger D. Journal of Neuroscience Research . 2016,第7期

机译：聚乙二醇融合修复可防止大鼠周围神经的神经支配准确性
4. Effect of Tocopheryl Polyethylene Glycol Succinate (TPGS) on Percutaneous Penetration of Minoxidilfrom Water/Ethanol/Polyethylene glycol (PEG) Solutions [C] . Ying-Ku Lin, Ming-Thau Sheu, Hsiu-O Ho Controlled Release Society annual meeting . 2004

机译：生育酚基聚乙二醇琥珀酸酯（TPGS）对米诺地尔从水/乙醇/聚乙二醇（PEG）溶液中渗透的影响
5. Use of polyethylene glycol (PEG) 8000 for rapid screening of potato (Solanum tuberosum L) genotypes for water stress tolerance. [D] . Suharjo, Usman Kris Joko. 2004

机译：聚乙二醇（PEG）8000用于快速筛选马铃薯（Solanum tuberosum L）基因型耐水胁迫性的用途。
6. A225 THE BOWEL CLEANSING NATIONAL INITIATIVE (BCLEAN): A HIGH-VOLUME SPLIT-DOSE POLYETHYLENE GLYCOL (PEG) PREPARATION VERSUS A LOW-VOLUME SPLIT-DOSE PEG SOLUTION. [O] . A N Barkun, M Martel, I L Epstein, 2019

机译：A225清洁大肠菌的国家计划（清洁）：大体积分剂量聚乙烯乙二醇（PEG）制备与小体积分剂量聚乙烯溶液的制备。
7. Polyethylene glycol (PEG)-fusion retards Wallerian degeneration and rapidly restores behaviors lost after nerve severance [O] . George D Bittner, Michelle Mikesh, Cameron L Ghergherehchi 2016

机译：聚乙二醇（pEG） - 融合可延缓Wallerian变性，并迅速恢复神经切断后失去的行为

Polyethylene glycol (PEG) and other bioactive solutions with neurorrhaphy for rapid and dramatic repair of peripheral nerve lesions by PEG-fusion

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