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首页> 外文期刊>Journal of obstetrics and gynaecology: the journal of the Institute of Obstetrics and Gynaecology >The potential effect of controlled ovarian hyperstimulation on follicular vascular perfusion: a study applying power Doppler ultrasonography within a treatment programme using donor sperm.
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The potential effect of controlled ovarian hyperstimulation on follicular vascular perfusion: a study applying power Doppler ultrasonography within a treatment programme using donor sperm.

机译：控制卵巢过度刺激对卵泡血管灌注的潜在效果：使用供体精子在治疗方面的应用电力多普勒超声检查。

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摘要

This was a prospective observational study to evaluate the effect of controlled ovarian hyperstimulation on follicular vascularity. A subjective grading system was applied to assess vascularity using transvaginal power Doppler ultrasonography on the day of insemination (32-36 hours post-HCG administration) in donor treatment cycles undergoing either controlled ovarian hyperstimulation (COH group) with gonadotrophin and intrauterine insemination or intracervical insemination with/without clomiphene stimulation (non-COH group). The incidence of follicles (81% vs. 53%; P < 0.05) as well as cycles (63% vs. 49%; P < 0.05) with uniformly high grade vascularity was significantly higher in treatments that had controlled ovarian hyperstimulation compared with unstimulated or clomiphene induced donor cycles. Pregnancy rates were higher and early pregnancy loss rates lower, in cycles with uniformly high grade follicular vascularity in both treatment groups compared with other vascularity grades. Using multiple logistic regression analysis, the only independent variable that was significantly related to pregnancy rates in this treatment programme was follicular vascularity. Controlled ovarian hyperstimulation appears to have an effect on follicular vascularity and this may contribute to improved outcome in donor insemination treatment programmes.
机译：这是评估对照卵巢过度刺激对卵泡血管性的影响的前瞻性观察研究。应用主体分级系统，用于使用经授精的经授精（32-36小时后HCG后给药后HCG给药后的32-36小时后的HCG给药后的32-36小时）的血管性进行评估血管性，所述卵巢治疗循环与促性腺激素和宫内生精或宫内节制物没有/没有克洛米己刺激（非COH组）。卵泡的发病率（81％vs.53％; p <0.05）以及均匀高级血管性的循环（63％vs.49％; p <0.05）在卵巢过度刺激与未刺激相比，治疗的治疗显着高。或克罗米芬诱导的供体循环。妊娠率较高，早期妊娠损失率降低，两种治疗组在两种治疗组中具有均匀高级卵泡血管的循环，与其他血管分级相比。使用多逻辑回归分析，该治疗计划中唯一与妊娠率明显相关的独立变量是滤泡血管性。受控的卵巢培养似乎似乎对滤泡血管性有影响，这可能有助于提高捐助授精治疗方案的结果。

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